Evidence map›Paper›PMID 36977696›Full record

ArticleNPJ microgravity2023

External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial.

Alessa L Boschert, Peter Gauger, Anja Bach, Darius Gerlach, Bernd Johannes, Jens Jordan, Zhili Li, David Elmenhorst, Andreas Bauer, Karina Marshall-Goebel and 3 more

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In one paragraph

Article in NPJ microgravity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessa L BoschertDepartment of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany. alessa.boschert@uk-koeln.de.ORCID http://orcid.org/0000-0002-0004-8966
Peter GaugerDepartment of Cardiovascular Aerospace Medicine, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Anja BachDepartment of Cardiovascular Aerospace Medicine, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Darius GerlachDepartment of Cardiovascular Aerospace Medicine, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.ORCID http://orcid.org/0000-0001-7044-6065
Bernd JohannesDepartment of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Jens JordanInstitute of Aerospace Medicine, German Aerospace Center (DLR) and Chair of Aerospace Medicine, Cologne, Germany.ORCID http://orcid.org/0000-0003-4518-0706
Zhili LiState Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, China.
David ElmenhorstForschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-2), Jülich, Germany.ORCID http://orcid.org/0000-0001-6137-416X
Andreas BauerForschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-2), Jülich, Germany.ORCID http://orcid.org/0000-0002-0117-3793
Karina Marshall-GoebelKBR, Houston, TX, USA.ORCID http://orcid.org/0000-0002-5240-7625
Jens TankDepartment of Cardiovascular Aerospace Medicine, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Jochen ZangeDepartment of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Jörn RittwegerDepartment of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.ORCID http://orcid.org/0000-0002-2223-8963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS.

Identifiers

PMID36977696
PMCPMC10050182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.