Evidence map›Paper›PMID 36977543›Full record

ReviewBMJ open2023

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global Burden of Disease Study 2019.

Rui Wang, Zhaoqi Li, Shaojun Liu, Decai Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 397 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
397citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

397 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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  4. To eradicate or not?Frontiers in medicine · 2026
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  9. Effects of a Low FODMAP Diet in Inflammatory Bowel Disease and Patient Experiences: A Mixed Methods Systematic Literature Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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337 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui WangDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.ORCID 0000-0002-5305-3283
Zhaoqi LiDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
Shaojun LiuDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
Decai ZhangDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China decaizhang@csu.edu.cn.ORCID 0000-0002-0099-5664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to provide the most updated estimates on the global burden of inflammatory bowel disease (IBD) to improve management strategies.

designWe extracted data from the Global Burden of Disease (GBD) 2019 database to evaluate IBD burden with different measures in 204 countries and territories from 1990 to 2019.

settingStudies from the GBD 2019 database generated by population-representative data sources identified through a literature review and research collaborations were included.

participantsPatients with an IBD diagnosis. OUTCOMES: Total numbers, age-standardised rates of prevalence, mortality and disability-adjusted life-years (DALYs), and their estimated annual percentage changes (EAPCs) were the main outcomes.

resultsIn 2019, there were approximately 4.9 million cases of IBD worldwide, with China and the USA having the highest number of cases (911 405 and 762 890 (66.9 and 245.3 cases per 100 000 people, respectively)). Between 1990 and 2019, the global age-standardised rates of prevalence, deaths and DALYs decreased (EAPCs=-0.66,-0.69 and -1.04, respectively). However, the age-standardised prevalence rate increased in 13 out of 21 GBD regions. A total of 147 out of 204 countries or territories experienced an increase in the age-standardised prevalence rate. From 1990 to 2019, IBD prevalent cases, deaths and DALYs were higher among females than among males. A higher Socio-demographic Index was associated with higher age-standardised prevalence rates.

conclusionsIBD will continue to be a major public health burden due to increasing numbers of prevalent cases, deaths and DALYs. The epidemiological trends and disease burden of IBD have changed dramatically at the regional and national levels, so understanding these changes would be beneficial for policy makers to tackle IBD.

Indexed as

Global Burden of DiseaseInflammatory Bowel DiseasesFemaleGlobal HealthHumansMalePrevalenceQuality-Adjusted Life YearsRisk FactorsEPIDEMIOLOGYGastroenterologyInflammatory bowel disease

Identifiers

PMID36977543
PMCPMC10069527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.