Evidence map›Paper›PMID 36977220›Full record

ArticleVeterinary sciences2023

Molecular Tracking of the Origin of Vesicular Stomatitis Outbreaks in 2004 and 2018, Ecuador.

David Vasco-Julio, Dayana Aguilar, Alexander Maldonado, Euclides de la Torre, Maria Soledad Cisneros-Montufar, Carlos Bastidas-Caldes, Juan-Carlos Navarro, Jacobus H de Waard

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Mcl-1 Protein and Viral Infections: A Narrative Review.International journal of molecular sciences · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

David Vasco-JulioOne Health Research Group, Facultad de Ingenierías y Ciencias Aplicadas, Carrera de Ingeniería en Biotecnología, Universidad de Las Américas, Quito 170530, Ecuador.ORCID 0000-0002-0546-8345
Dayana AguilarOne Health Research Group, Facultad de Ciencias Veterinarias, Universidad de Las Américas, Quito 170530, Ecuador.ORCID 0000-0002-1531-6791
Alexander MaldonadoDirección de Diagnóstico Animal, Agencia de Regulación y Control Fito y Zoosanitario, Agrocalidad, Quito 170518, Ecuador.ORCID 0000-0002-5583-2141
Euclides de la TorreDirección de Diagnóstico Animal, Agencia de Regulación y Control Fito y Zoosanitario, Agrocalidad, Quito 170518, Ecuador.
Maria Soledad Cisneros-MontufarGroup of Emerging and Neglected Diseases, Ecoepidemiology and Biodiversity, Health Sciences Faculty, Universidad Internacional SEK, Quito 170521, Ecuador.ORCID 0000-0002-7921-9448
Carlos Bastidas-CaldesOne Health Research Group, Facultad de Ingenierías y Ciencias Aplicadas, Carrera de Ingeniería en Biotecnología, Universidad de Las Américas, Quito 170530, Ecuador.ORCID 0000-0002-5364-7700
Juan-Carlos NavarroGroup of Emerging and Neglected Diseases, Ecoepidemiology and Biodiversity, Health Sciences Faculty, Universidad Internacional SEK, Quito 170521, Ecuador.ORCID 0000-0002-7692-4248
Jacobus H de WaardOne Health Research Group, Facultad de Ciencias Veterinarias, Universidad de Las Américas, Quito 170530, Ecuador.ORCID 0000-0003-4118-1015
Universidad de Las Américas · ECInstituto Nacional de Biodiversidad · ECUniversidad Internacional SEK · EC

Funding

Universidad de Las Américas 5000
6 · The paper itself

Abstract

The Vesicular Stomatitis Virus (VSV) is an arbovirus causing vesicular stomatitis (VS) in livestock. There are two serotypes recognized: New Jersey (VSNJV) and Indiana (VSIV). The virus can be transmitted directly by contact or by vectors. In 2018, Ecuador experienced an outbreak of Vesicular Stomatitis (VS) in cattle, caused by VSNJV and VSVIV, with 399 cases reported distributed over 18 provinces. We determined the phylogenetic relationships among 67 strains. For the construction of phylogenetic trees, the viral phosphoprotein gene was sequenced, and trees were constructed based on the Maximum Likelihood method using 2004 outbreak strains from Ecuador (GenBank) and the 2018 sequences (this article). We built a haplotype network for VSNJV to trace the origin of the 2004 and 2018 epizootics through topology and mutation connections. These analyses suggest two different origins, one related to the 2004 outbreak and the other from a transmission source in 2018. Our analysis also suggests different transmission patterns; several small and independent outbreaks, most probably transmitted by vectors in the Amazon, and another outbreak caused by the movement of livestock in the Andean and Coastal regions. We recommend further research into vectors and vertebrate reservoirs in Ecuador to clarify the mechanisms of the reemergence of the virus.

Indexed as

molecular epidemiologyoutbreakphylogenyvesicular stomatitis virus

Identifiers

PMID36977220
PMCPMC10057135
OpenAlexW4322503467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.