ArticleTropical medicine and infectious disease2023
Natural History of Hepatosplenic Schistosomiasis (HSS) Non-Cirrhotic Portal Hypertension (NCPH): Influence of Gastrointestinal Bleeding and Decompensation in Prognosis.
Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Ultrasound and point shear-wave elastography assessment for predicting esophageal varices in schistosomiasis-associated non-cirrhotic portal hypertension.Abdominal radiology (New York) · 2026Article
- Liver and spleen ultrasonography and elastography are useful for identifying a history of upper gastrointestinal bleeding in patients with schistosomiasis.BMC infectious diseases · 2026Article
- Survival of patients with hepatopulmonary syndrome related to cirrhotic and non-cirrhotic (schistosomiasis) portal hypertension.World journal of hepatology · 2025Article
- Porto Sinusoidal Vascular Disorder: A Case Report.International medical case reports journal · 2025Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatosplenic schistosomiasis (HSS) is a peculiar form of non-cirrhotic portal hypertension (NCPH). Although HSS patients present normal hepatic function, some evolve signs of hepatocellular failure and features of decompensated cirrhosis. The natural history of HSS-NCPH is unknown.
methodsA retrospective study was conducted that evaluated patients who fulfilled clinical-laboratorial criteria for HSS.
resultsA total of 105 patients were included. Eleven patients already presented with decompensated disease and had lower transplant-free survival at 5 years than those without (61% vs. 95%,
conclusionHSS is characterized by multiple episodes of GI bleeding, a high probability of decompensation and reduced survival at the end of the first decade. Decompensation is more common in patients with varicose esophageal bleeding and is associated with lower survival.
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