Evidence map›Paper›PMID 36977115›Full record

ArticleToxins2023

Functional and Proteomic Insights into Aculeata Venoms.

Daniel Dashevsky, Kate Baumann, Eivind A B Undheim, Amanda Nouwens, Maria P Ikonomopoulou, Justin O Schmidt, Lilin Ge, Hang Fai Kwok, Juanita Rodriguez, Bryan G Fry

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Toxins · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Daniel DashevskyAustralian National Insect Collection, Commonwealth Scientific & Industrial Research Organisation, Canberra, ACT 2601, Australia.ORCID 0000-0003-4346-7252
Kate BaumannVenom Evolution Lab, School of Biological Sciences, The University of Queensland, St. Lucia, QLD 4072, Australia.ORCID 0000-0002-7516-3977
Eivind A B UndheimCentre for Ecological and Evolutionary Synthesis, Department of Bioscience, University of Oslo, N-0316 Oslo, Norway.ORCID 0000-0002-8667-3999
Amanda NouwensSchool of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, QLD 4072, Australia.ORCID 0000-0003-4069-8266
Maria P IkonomopoulouTranslational Venomics Group, Madrid Institute for Advanced Studies in Food, 4075 Madrid, Spain.ORCID 0000-0001-7739-080X
Justin O SchmidtSouthwestern Biological Institute, 1961 W. Brichta Dr., Tucson, AZ 85745, USA.ORCID 0000-0002-3363-3846
Lilin GeState Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210046, China.
Hang Fai KwokInstitute of Translational Medicine, Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau.ORCID 0000-0002-6349-4517
Juanita RodriguezAustralian National Insect Collection, Commonwealth Scientific & Industrial Research Organisation, Canberra, ACT 2601, Australia.ORCID 0000-0001-9922-1978
Bryan G FryVenom Evolution Lab, School of Biological Sciences, The University of Queensland, St. Lucia, QLD 4072, Australia.ORCID 0000-0001-6661-1283
The University of Queensland · AUCommonwealth Scientific and Industrial Research Organisation · AUMadrid Institute for Advanced Studies · ESNanjing University of Chinese Medicine · CNUniversity of Macau · MOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aculeate hymenopterans use their venom for a variety of different purposes. The venom of solitary aculeates paralyze and preserve prey without killing it, whereas social aculeates utilize their venom in defence of their colony. These distinct applications of venom suggest that its components and their functions are also likely to differ. This study investigates a range of solitary and social species across Aculeata. We combined electrophoretic, mass spectrometric, and transcriptomic techniques to characterize the compositions of venoms from an incredibly diverse taxon. In addition, in vitro assays shed light on their biological activities. Although there were many common components identified in the venoms of species with different social behavior, there were also significant variations in the presence and activity of enzymes such as phospholipase A

Indexed as

HymenopteraToxins, BiologicalAnimalsBeesProteomicsTranscriptomeVenomsToxins, BiologicalVenomsAculeatacytotoxicityproteomicssocialityvenom

Identifiers

PMID36977115
PMCPMC10053895
OpenAlexW4327715146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.