Evidence map›Paper›PMID 36977089›Full record

ArticleToxins2023

Effect of Hydrogen Sulfide on Essential Functions of Polymorphonuclear Leukocytes.

Sarah Farahat, Salome Kherkheulidze, Stephan Nopp, Alexander Kainz, Margherita Borriello, Alessandra F Perna, Gerald Cohen

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Impact of increasedJournal of oral microbiology · 2025
    Article
  6. Perspectives on the involvement of the gut microbiota in salt-sensitive hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  7. Review
  8. Plants and Mushrooms as Possible New Sources of HInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sarah FarahatDepartment of Nephrology and Dialysis, Medical University of Vienna, A-1090 Vienna, Austria.
Salome KherkheulidzeDepartment of Nephrology and Dialysis, Medical University of Vienna, A-1090 Vienna, Austria.
Stephan NoppDepartment of Nephrology and Dialysis, Medical University of Vienna, A-1090 Vienna, Austria.ORCID 0000-0002-4504-482X
Alexander KainzDepartment of Nephrology and Dialysis, Medical University of Vienna, A-1090 Vienna, Austria.
Margherita BorrielloDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Alessandra F PernaDepartment of Translational Medical Science, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0003-4048-9392
Gerald CohenDepartment of Nephrology and Dialysis, Medical University of Vienna, A-1090 Vienna, Austria.
Medical University of Vienna · ATUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired polymorphonuclear leukocyte (PMNL) functions contribute to increased infections and cardiovascular diseases in chronic kidney disease (CKD). Uremic toxins reduce hydrogen sulfide (H

Indexed as

Hydrogen SulfideNeutrophilsAllyl CompoundsCysteineDisulfidesEscherichia coliMorpholinesOrganothiophosphorus CompoundsPhosphatidylinositol 3-KinasesSulfidesAllyl CompoundsCysteinediallyl disulfidediallyl trisulfideDisulfidesGYY 4137Hydrogen SulfideMorpholinesOrganothiophosphorus CompoundsPhosphatidylinositol 3-Kinasessodium bisulfidesodium sulfideSulfidesapoptosischronic kidney diseasehydrogen sulfideimmunologyinflammationpolymorphonuclear leukocytessignal transductionuremic toxins

Identifiers

PMID36977089
PMCPMC10058000
OpenAlexW4323314616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.