Evidence map›Paper›PMID 36977043›Full record

ArticleToxics2023

Electronic Cigarette Use during Pregnancy: Is It Harmful?

M J Ruzmyn Vilcassim, Samuel Stowe, Rachel Majumder, Akila Subramaniam, Rachel G Sinkey

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Toxicity and Appeal of Flavoured E-Cigarettes and Flavour Ban Outcomes: A Narrative Review.International journal of environmental research and public health · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Intrapartum Electronic Cigarette Use and Birth Outcomes: Evidence from a Population-Based Study.International journal of environmental research and public health · 2024
    Article
  15. Fetal Growth Following Electronic Cigarette Use in Pregnancy.International journal of environmental research and public health · 2024
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M J Ruzmyn VilcassimDepartment of Environmental Health Sciences, School of Public Health, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID 0000-0003-3695-815X
Samuel StoweDepartment of Environmental Health Sciences, School of Public Health, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Rachel MajumderSchool of Health Professions, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Akila SubramaniamCenter for Women's Reproductive Health, Division of Maternal Fetal Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Rachel G SinkeyCenter for Women's Reproductive Health, Division of Maternal Fetal Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
University of Alabama at Birmingham · US

Funding

The ACHIEVE Trial: Achieving longer gestation in preeclampsia via antihypertensive therapy.K23HL159331 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Rachel G Sinkey · 2022 to 2026
$884k
NHLBI NIH HHS K23 HL159331
6 · The paper itself

Abstract

Although combustible cigarette smoking rates have declined in recent years, alternative tobacco product use, particularly electronic cigarette use ("vaping"), has increased among young adults. Recent studies indicate that vaping during pregnancy is on the rise, possibly due to the perception that it is a safer alternative to combustible cigarette smoking. However, e-cigarette aerosols may contain several newer, potentially toxic compounds, including some known developmental toxicants that may adversely impact both the mother and the fetus. However, there is paucity of studies that have examined the effects of vaping during pregnancy. While the adverse perinatal outcomes of cigarette smoking during pregnancy are well established, the specific risks associated with inhaling vaping aerosols during pregnancy requires more research. In this article, we discuss the existing evidence and knowledge gaps on the risks of vaping during pregnancy. Studies that investigate vaping-associated systemic exposure and its effects (i.e., biomarker analyses) and maternal and neonatal clinical health outcomes are needed to reach more robust conclusions. We particularly emphasize the need to go beyond comparative studies with cigarettes, and advocate for research that objectively evaluates the safety of e-cigarettes and other alternative tobacco products.

Indexed as

biomarkerselectronic cigarettesperinatal healthpregnancyvaping

Identifiers

PMID36977043
PMCPMC10058591
OpenAlexW4327954594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.