Evidence map›Paper›PMID 36977024›Full record

ReviewToxics2023

Adverse Childhood Experiences (ACEs) and Environmental Exposures on Neurocognitive Outcomes in Children: Empirical Evidence, Potential Mechanisms, and Implications.

Margaret Gladieux, Nathan Gimness, Bianca Rodriguez, Jianghong Liu

Abstract readReview
In one paragraph

Review in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margaret GladieuxDepartment of Family and Community Health, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nathan GimnessDepartment of Family and Community Health, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, USA.
Bianca RodriguezDepartment of Family and Community Health, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jianghong LiuDepartment of Family and Community Health, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-8405-6153

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Steer and trees summer research programsR25ES021649 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI FIELD, JEFFREY M · 2013 to 2022
$830k
NIEHS NIH HHS P30 ES013508NIEHS NIH HHS R25 ES021649
6 · The paper itself

Abstract

The purpose of this article is to examine the current literature regarding the relationship between adverse childhood experiences (ACEs) and environmental exposures. Specifically, the paper will focus on how this relationship between ACEs and physical environmental factors impacts the neurocognitive development of children. With a comprehensive literary search focusing on ACEs, inclusive of socioeconomic status (SES), and environmental toxins common in urban environments, the paper explores how these factors contribute to cognitive outcomes that are associated with the environment and childhood nurturing. The relationship between ACEs and environmental exposures reveals adverse outcomes in children's neurocognitive development. These cognitive outcomes include learning disabilities, lowered IQ, memory and attention problems, and overall poor educational outcomes. Additionally, potential mechanisms of environmental exposures and children's neurocognitive outcomes are explored, referencing data from animal studies and evidence from brain imaging studies. This study further analyzes the current gaps in the literature, such as the lack of data focusing on exposure to environmental toxicants resulting from experiencing ACEs and discusses the research and social policy implications of ACEs and environmental exposure in the neurocognitive development of children.

Indexed as

adverse childhood experiences (ACEs)environmental exposureneurocognitionsocioeconomic status (SES)toxicants

Identifiers

PMID36977024
PMCPMC10055754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.