Evidence map›Paper›PMID 36976682›Full record

ArticleNursing reports (Pavia, Italy)2023

Outcome of Ivermectin in Cancer Treatment: An Experience in Loja-Ecuador.

Yuliana Jiménez-Gaona, Oscar Vivanco-Galván, Gonzalo Morales-Larreategui, Andrea Cabrera-Bejarano, Vasudevan Lakshminarayanan

Open access · goldAbstract read
In one paragraph

Article in Nursing reports (Pavia, Italy), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Yuliana Jiménez-GaonaDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano Alto S/N, Loja PC1101608, Ecuador.ORCID 0000-0001-7155-5546
Oscar Vivanco-GalvánDepartamento de Ciencias Biológicas y Agropecuarias, Universidad Técnica Particular de Loja (UTPL), San Cayetano Alto S/N, Loja PC1101608, Ecuador.ORCID 0000-0001-7799-6297
Gonzalo Morales-LarreateguiDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano Alto S/N, Loja PC1101608, Ecuador.
Andrea Cabrera-BejaranoDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano Alto S/N, Loja PC1101608, Ecuador.
Vasudevan LakshminarayananTheoretical and Experimental Epistemology Lab, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L3G1, Canada.ORCID 0000-0002-3473-1245
Universidad Técnica Particular de Loja · ECUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Cancer is one of the leading causes of death worldwide, and trends in cancer incidence and mortality are increasing over last years in Loja-Ecuador. Cancer treatment is expensive because of social and economic issues which force the patients to look for other alternatives. One such alternative treatment is ivermectin-based antiparasitic, which is commonly used in treating cattle. This paper analyzed ivermectin use as cancer treatment in the rural area of the Loja province and the medical opinion regarding the use of ivermectin in humans. (2) Methods: The study used a mixed methodology using different sampling techniques such as observation, surveys, and interviews. (3) Results: The main findings show that 19% of the participants diagnosed with cancer take medicines based on ivermectin as alternative therapy to the cancer control and treatment without leaving treatment such as chemotherapy, radiotherapy, or immunotherapy, while 81% use it to treat other diseases. (4) Conclusions: Finally, we identify that the interviewed not only use IVM as anticancer treatment, but it is also used as a treatment against other diseases. Although the participants' opinions indicate that they feel improvements in their health after the third dose, the specialist considers that there is no authorization to prescribe these alternative treatments. In addition, they confirmed that currently, there is no scientific knowledge about the application of these treatments in humans and they do not recommend their application. Thus, the anticancer mechanism of ivermectin remains to be further investigated; therefore, we consider that it is important to continue with this research by proposing a new stage to evaluate and determine the pharmacological action of this type of drug through an in vitro study in different cultures of cancer cells.

Indexed as

antiparasiticcancerivermectintreatment

Identifiers

PMID36976682
PMCPMC10054244
OpenAlexW4321596241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.