Evidence map›Paper›PMID 36976676›Full record

ArticleACS synthetic biology2023

Inducible Synthetic Growth Regulation Using the ClpXP Proteasome Enhances cis,cis-Muconic Acid and Glycolic Acid Yields in

Natalia Kakko, Anssi Rantasalo, Tino Koponen, Virve Vidgren, Matti Kannisto, Natalia Maiorova, Heli Nygren, Dominik Mojzita, Merja Penttilä, Paula Jouhten

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Natalia KakkoVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Anssi RantasaloVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Tino KoponenVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Virve VidgrenVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Matti KannistoVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Natalia MaiorovaVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Heli NygrenVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Dominik MojzitaVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.ORCID 0000-0001-6078-4503
Merja PenttiläVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.
Paula JouhtenVTT Technical Research Centre of Finland Ltd, Espoo 02044 VTT, Finland.ORCID 0000-0003-1075-7448
VTT Technical Research Centre of Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineered microbial cells can produce sustainable chemistry, but the production competes for resources with growth. Inducible synthetic control over the resource use would enable fast accumulation of sufficient biomass and then divert the resources to production. We developed inducible synthetic resource-use control over

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsGlycolatesMetabolic EngineeringProteasome Endopeptidase ComplexSorbic AcidGlycolatesglycolic acidmuconic acidProteasome Endopeptidase ComplexSaccharomyces cerevisiae ProteinsSorbic Acidcis,cis-muconic acidClpXP proteasomeglycolic acidSaccharomyces cerevisiaesynthetic regulation

Identifiers

PMID36976676
PMCPMC10127448
OpenAlexW4361190981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.