Evidence map›Paper›PMID 36976586›Full record

ArticleThe western journal of emergency medicine2023

Characteristics of Emergency Medicine Specimen Bank Participants Compared to the Overall Emergency Department Population.

Alexis Vest, Brandon Sonn, Richie Puls, Cosby Arnold, Zach Devney, Arwah Ahmed, Olivia Pallisard, Andrew A Monte

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Article in The western journal of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexis VestUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Brandon SonnUniversity of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
Richie PulsUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Cosby ArnoldUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Zach DevneyUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Arwah AhmedUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Olivia PallisardUniversity of Colorado School of Medicine, Department of Emergency Medicine, Aurora, Colorado.
Andrew A MonteUniversity of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PERSONALIZING EMERGENCY/ACUTE THERAPEUTICS UTILIZING SYSTEMS BIOLOGY (PEGASUS)R35GM124939 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MONTE, ANDREW ALBERT · 2017 to 2021
$2.1M
A COVID-19 Pulmonary Outcome Clinical Prediction Rule Using EpigeneticsF32HL160123 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ARNOLD, COSBY · 2021 to 2022
$157k
NCATS NIH HHS UL1 TR001082NHLBI NIH HHS F32 HL160123NIGMS NIH HHS R35 GM124939
6 · The paper itself

Abstract

introductionBiorepositories lack diversity both demographically and with regard to the clinical complaints of patients enrolled. The Emergency Medicine Specimen Bank (EMSB) seeks to enroll a diverse cohort of patients for discovery research in acute care conditions. Our objective in this study was to determine the differences in demographics and clinical complaints between participants in the EMSB and the overall emergency department (ED) population.

methodsThis was a retrospective analysis of participants of the EMSB and the entire UCHealth at University of Colorado Anschutz Medical Center (UCHealth AMC) ED population across three periods: peri-EMSB; post-EMSB; and COVID-19. We compared patients consented to the EMSB to the entire ED population to determine differences in age, gender, ethnicity, race, clinical complaints, and severity of illness. We used chi-square tests to compare categorical variables and the Elixhauser Comorbidity Index to determine differences in the severity of illness between the groups.

resultsBetween February 5, 2018-January 29, 2022, there were 141,670 consented encounters in the EMSB, representing 40,740 unique patients and over 13,000 blood samples collected. In that same time, the ED saw approximately 188,402 unique patients for 387,590 encounters. The EMSB had significantly higher rates of participation from the following: patients 18-59 years old (80.3% vs 77.7%); White patients (52.3% vs 47.8%), and women (54.8% vs 51.1%) compared to the overall ED population. The EMSB had lower rates of participation from patients ≥70 years, Hispanic patients, Asian patients, and men. The EMSB population had higher mean comorbidity scores. During the six months after Colorado's first COVID-19 case, the rate of consented patients and samples collected increased. The odds of consent during the COVID-19 study period were 1.32 (95% CI 1.26-1.39), and the odds of sample capture were 2.19 (95% CI 2.0-2.41).

conclusionThe EMSB is representative of the overall ED population for most demographics and clinical complaints.

Indexed as

Emergency MedicinePatient ParticipationTissue BanksAcute DiseaseAdolescentAdultCOVID-19Emergency Service, HospitalFemaleHumansMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID36976586
PMCPMC10047721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.