ReviewCurrent osteoporosis reports2023
Exercise to Prevent and Manage Frailty and Fragility Fractures.
Review in Current osteoporosis reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07572851 (Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care), which is not on this map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Vitamin D Supplementation and the Incidence of Fractures in the Elderly Healthy Population: A Meta-analysis of Randomized Controlled Trials.Journal of general internal medicine · 2024Pooled it
- Effectiveness of fracture liaison service in reducing the risk of secondary fragility fractures in adults aged 50 and older: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Pooled it
- Effectiveness of a home-based physical exercise intervention in patients with hip fragility fractures: a randomized controlled trial.Scientific reports · 2026Trial
- The effectiveness of virtual reality exercise games on balance functions and fear of falling in women with osteoporosis.Rheumatology international · 2024Trial
- A retrospective study on the application of unilateral epidural anesthesia in older patients with hip fracture.BMC geriatrics · 2026Article
- Article
- Determinants of hospital length of stay in older adults after hip fracture: a prospective cohort study.BMC geriatrics · 2026Observational
- Physical Exercise After Fragility Fractures: A Systematic Review and Meta-Analysis of Function and Morbidity.Journal of clinical medicine · 2026Review
- Association of frailty trajectories with osteoporosis and hip fracture in an older female population.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Association of frailty with fragility fractures and all‑cause mortality in adults: evidence from the National Health and Nutrition Examination Survey.BMC musculoskeletal disorders · 2026Article
- Use of DXA-derived 3D-modeling, as implemented by 3D-Shaper, for the assessment of fracture risk in a population-based setting.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Longer sedentary time is associated with increased risk of low pelvic bone density.BMC public health · 2026Article
- Clinical, functional, and immunological profiles across frailty subgroups in maintenance hemodialysis patient.Frontiers in endocrinology · 2026Observational
- Assessment of the effects of whole-body muscle and fat mass on bone mineral content based on 628 DXA datasets.Frontiers in endocrinology · 2026Article
- Multidimensional and Multidisciplinary Management of Heart Failure Patients with Frailty.Cardiac failure review · 2026Review
- Malnutrition, Frailty, and High Fall Risk in Older Adults: Examining Their Interactive Effects in a Cross-Sectional Study.Clinical interventions in aging · 2026Article
- The prospective association between high-density lipoprotein (HDL) cholesterol and risk of incident fractures in the general population.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- The Impact of Physical Education Attendance and Diet on Bone Mineralization in Adolescents.Nutrients · 2025Article
- Bone Health in Metabolic Syndrome-Is It a Neglected Aspect of Dysmetabolic-Related Diseases?Journal of clinical medicine · 2025Review
- Regulation of Renal and Extrarenal Calcitriol Synthesis and Its Clinical Implications.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review identifies exercise-based recommendations to prevent and manage frailty and fragility fractures from current clinical practice guidelines. We also critically assess recently published literature in relation to exercise interventions to mitigate frailty and fragility fractures. RECENT
findingsMost guidelines presented similar recommendations that included the prescription of individually tailored, multicomponent exercise programs, discouragement of prolonged sitting and inactivity, and combining exercise with optimal nutrition. To target frailty, guidelines recommend supervised progressive resistance training (PRT). For osteoporosis and fragility fractures, exercise should include weight-bearing impact activities and PRT to target bone mineral density (BMD) at the hip and spine, and also incorporate balance and mobility training, posture exercises, and functional exercise relevant to activities of daily living to reduce falls risk. Walking as a singular intervention has limited benefits for frailty and fragility fracture prevention and management. Current evidence-based clinical practice guidelines for frailty, osteoporosis, and fracture prevention recommend a multifaceted and targeted approach to optimise muscle mass, strength, power, and functional mobility as well as BMD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.