Evidence map›Paper›PMID 36976442›Full record

ArticleMycopathologia2023

Insights into Changing Dermatophyte Spectrum in India Through Analysis of Cumulative 161,245 Cases Between 1939 and 2021.

Pawan Kumar, S Ramachandran, Shukla Das, S N Bhattacharya, Bhupesh Taneja

Abstract read
In one paragraph

Article in Mycopathologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Journal of clinical microbiology · 2026
    Article
  3. Article
  4. Article
  5. The emergence of superficial dermatophytosis due toJournal of clinical microbiology · 2026
    Article
  6. Article
  7. Article
  8. Emerging antifungal resistance inEmerging microbes & infections · 2025
    Article
  9. Article
  10. Integrating Machine Learning and Molecular Methods forPathogens (Basel, Switzerland) · 2025
    Article
  11. National Belgian Study on Terbinafine Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Journal of fungi (Basel, Switzerland) · 2024
    Article
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pawan KumarCSIR-Institute of Genomics and Integrative Biology(CSIR-IGIB), New Delhi, 110025, India.
S RamachandranCSIR-Institute of Genomics and Integrative Biology(CSIR-IGIB), New Delhi, 110025, India.
Shukla DasUCMS-GTB, Hospital, Dilshad Garden, Delhi, 110095, India.
S N BhattacharyaDr. Babasaheb Ambedkar Medical College and Hospital, Delhi, 110085, India.
Bhupesh TanejaCSIR-Institute of Genomics and Integrative Biology(CSIR-IGIB), New Delhi, 110025, India. btaneja@igib.res.in.ORCID http://orcid.org/0000-0001-8342-7541

Funding

Department of Biotechnology, Govt of India BT/PR20790/MED/29/1130/2016
6 · The paper itself

Abstract

Dermatophytosis is one of the most common superficial infections of the skin affecting nearly one-fifth of the world population at any given time. With nearly 30% of worldwide terbinafine-resistance cases in Trichophyton mentagrophytes/Trichophyton interdigitale and Trichophyton rubrum reported from India in recent years, there is a significant burden of the emerging drug resistance epidemic on India. Here, we carry out a comprehensive retrospective analysis of dermatophytosis in India using 1038 research articles pertaining to 161,245 cases reported from 1939 to 2021. We find that dermatophytosis is prevalent in all parts of the country despite variable climatic conditions in different regions. Our results show T. rubrum as the most prevalent until 2015, with a sudden change in dermatophyte spectrum towards T. mentagrophytes/T. interdigitale complex since then. We also carried out an 18S rRNA-based phylogenetics and an average nucleotide identity-and single nucleotide polymorphism-based analysis of available whole genomes and find very high relatedness among the prevalent dermatophytes, suggesting geographic specificity. The comprehensive epidemiological and phylogenomics analysis of dermatophytosis in India over the last 80 years, presented here, would help in region-specific prevention, control and treatment of dermatophyte infections, especially considering the large number of emerging resistance cases.

Indexed as

ArthrodermataceaeTineaHumansIndiaRetrospective StudiesTrichophytonDermatophytosisEpidemiologyLiterature-miningPhylogenomics

Identifiers

PMID36976442
PMCPMC10307719

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.