Evidence map›Paper›PMID 36976357›Full record

Trial reportGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Comparison of the influence of alcohol and cannabis on the dynamics of the accommodative response.

Miriam Casares-López, Sonia Ortiz-Peregrina, Carolina Ortiz, José J Castro-Torres, Rosario G Anera

Open access · greenAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Miriam Casares-LópezDepartment of Optics, Laboratory of Vision Sciences and Applications, Faculty of Sciences, University of Granada, Av. Fuente Nueva s/n, Mecenas Building, 18003, Granada, Spain. clmiriam@ugr.es.ORCID http://orcid.org/0000-0003-2767-4913
Sonia Ortiz-PeregrinaDepartment of Optics, Laboratory of Vision Sciences and Applications, Faculty of Sciences, University of Granada, Av. Fuente Nueva s/n, Mecenas Building, 18003, Granada, Spain.
Carolina OrtizDepartment of Optics, Laboratory of Vision Sciences and Applications, Faculty of Sciences, University of Granada, Av. Fuente Nueva s/n, Mecenas Building, 18003, Granada, Spain.
José J Castro-TorresDepartment of Optics, Laboratory of Vision Sciences and Applications, Faculty of Sciences, University of Granada, Av. Fuente Nueva s/n, Mecenas Building, 18003, Granada, Spain.
Rosario G AneraDepartment of Optics, Laboratory of Vision Sciences and Applications, Faculty of Sciences, University of Granada, Av. Fuente Nueva s/n, Mecenas Building, 18003, Granada, Spain.
Universidad de Granada · ES

Funding

FEDER/Junta de Andalucía-Consejería de Transformación Económica, Industria, Conocimiento y Universidades A-FQM-532-UGR20MCIN/ AEI/10.13039/501100011033 PID2020-115184RB-I00
6 · The paper itself

Abstract

purposeTo assess and compare the changes produced by the two most commonly used substances, alcohol and cannabis, on accommodation dynamics.

methodsA total of 38 young participants (19 females) were enrolled in the study. They were assigned to two groups: a cannabis group (N = 19) and an alcohol group. Participants in the cannabis group underwent two randomized sessions: a baseline session and a session after smoking a cigarette. Participants in the alcohol group underwent three randomized sessions: a baseline session, a session after the intake of 300 ml of red wine (Alcohol 1), and other after the ingestion of 450 ml of wine (Alcohol 2). For the accommodation assessment, the open-field autorefractor WAM-5500 was used.

resultsThe decrease of the mean velocity of the accommodative response produced by Alcohol 2 condition was significantly greater than that observed for Alcohol 1 and Cannabis (p = 0.046). The direction of the accommodation (near-distance and distance-near) had no effect on the deterioration of the accommodation dynamics following substance use. The target distance had a significant effect on the decrease of the mean velocity following substance use (p = 0.002). The decrease of the amplitude of the accommodative response was associated with a decrease of the peak velocity (p = 0.004) and the increase of the accommodative lag (p < 0.001).

conclusionsA moderate-high dose of alcohol impairs accommodation dynamics to a greater extent that lower dose of alcohol or smoked cannabis. The deterioration of the accommodation mean speed was higher for a shorter target distance.

Indexed as

CannabisOptometryAccommodation, OcularFemaleHumansAccommodation dynamicsAccommodative lagAccommodative responseAlcohol consumptionCannabis useTarget distance

Identifiers

PMID36976357
OpenAlexW4361191135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.