Evidence map›Paper›PMID 36976196›Full record

ReviewMarine drugs2023

Chitosan-Based Biomaterials: Insights into Chemistry, Properties, Devices, and Their Biomedical Applications.

Simona Petroni, Irene Tagliaro, Carlo Antonini, Massimiliano D'Arienzo, Sara Fernanda Orsini, João F Mano, Virginia Brancato, João Borges, Laura Cipolla

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Simona PetroniDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0002-4570-6846
Irene TagliaroDepartment of Materials Science, University of Milano-Bicocca, 20125 Milano, Italy.ORCID 0000-0002-3146-5674
Carlo AntoniniDepartment of Materials Science, University of Milano-Bicocca, 20125 Milano, Italy.ORCID 0000-0002-4975-4001
Massimiliano D'ArienzoDepartment of Materials Science, University of Milano-Bicocca, 20125 Milano, Italy.
Sara Fernanda OrsiniDepartment of Materials Science, University of Milano-Bicocca, 20125 Milano, Italy.
João F ManoCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-2342-3765
Virginia BrancatoDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0002-9992-4769
João BorgesCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-0126-8482
Laura CipollaDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0003-2678-8329
University of Milano-Bicocca · ITUniversity of Aveiro · PT

Funding

Cariplo Foundation BIOSTAR-PACK project (2020-0993)FCT for the individual Assistant Researcher contract under the Scientific Employment Stimulus - Individual Call. 2020.00758.CEECINDnational funds through the FCT/MEC (PIDDAC) UIDB/50011/2020, UIDP/50011/2020 and LA/P/0006/2020Programa Operacional Regional do Centro and Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior project "SUPRASORT" PTDC/QUI-OUT/30658/2017, CENTRO-01-0145-FEDER-030658
6 · The paper itself

Abstract

Chitosan is a marine-origin polysaccharide obtained from the deacetylation of chitin, the main component of crustaceans' exoskeleton, and the second most abundant in nature. Although this biopolymer has received limited attention for several decades right after its discovery, since the new millennium chitosan has emerged owing to its physicochemical, structural and biological properties, multifunctionalities and applications in several sectors. This review aims at providing an overview of chitosan properties, chemical functionalization, and the innovative biomaterials obtained thereof. Firstly, the chemical functionalization of chitosan backbone in the amino and hydroxyl groups will be addressed. Then, the review will focus on the bottom-up strategies to process a wide array of chitosan-based biomaterials. In particular, the preparation of chitosan-based hydrogels, organic-inorganic hybrids, layer-by-layer assemblies, (bio)inks and their use in the biomedical field will be covered aiming to elucidate and inspire the community to keep on exploring the unique features and properties imparted by chitosan to develop advanced biomedical devices. Given the wide body of literature that has appeared in past years, this review is far from being exhaustive. Selected works in the last 10 years will be considered.

Indexed as

ChitosanAnimalsBiocompatible MaterialsChitinCrustaceaPolysaccharidesTissue EngineeringBiocompatible MaterialsChitinChitosanPolysaccharides3D printingchitosanchitosan-based materialsdrug deliveryhydrogelslayer-by-layer devicesmarine-origin polysaccharidesorganic–inorganic hybridsregenerative medicinetissue engineering

Identifiers

PMID36976196
PMCPMC10059909
OpenAlexW4322503060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.