Evidence map›Paper›PMID 36976049›Full record

ReviewJournal of functional biomaterials2023

Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review.

Fabio Distefano, Salvatore Pasta, Gabriella Epasto

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. A review of 3D printed medical implant design.3D printing in medicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood-Gas Exchange.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fabio DistefanoDepartment of Engineering, University of Messina, C.da Di Dio, 98166 Messina, Italy.
Salvatore PastaDepartment of Engineering, University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0002-4841-2560
Gabriella EpastoDepartment of Engineering, University of Messina, C.da Di Dio, 98166 Messina, Italy.ORCID 0000-0003-1372-5871

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progress in additive manufacturing has remarkably increased the application of lattice materials in the biomedical field for the fabrication of scaffolds used as bone substitutes. Ti6Al4V alloy is widely adopted for bone implant application as it combines both biological and mechanical properties. Recent breakthroughs in biomaterials and tissue engineering have allowed the regeneration of massive bone defects, which require external intervention to be bridged. However, the repair of such critical bone defects remains a challenge. The present review collected the most significant findings in the literature of the last ten years on Ti6Al4V porous scaffolds to provide a comprehensive summary of the mechanical and morphological requirements for the osteointegration process. Particular attention was given on the effects of pore size, surface roughness and the elastic modulus on bone scaffold performances. The application of the Gibson-Ashby model allowed for a comparison of the mechanical performance of the lattice materials with that of human bone. This allows for an evaluation of the suitability of different lattice materials for biomedical applications.

Indexed as

additive manufacturingbone tissue engineeringlattice structuresmechanical propertiesscaffoldstitanium alloy

Identifiers

PMID36976049
PMCPMC10059040

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.