Evidence map›Paper›PMID 36975959›Full record

ArticleInsects2023

Dehydration Alters Transcript Levels in the Mosquito Midgut, Likely Facilitating Rapid Rehydration following a Bloodmeal.

Christopher J Holmes, Elliott S Brown, Dhriti Sharma, Matthew Warden, Atit Pathak, Blaine Payton, Quynh Nguyen, Austin Spangler, Jaishna Sivakumar, Jacob M Hendershot and 1 more

Abstract read
In one paragraph

Article in Insects, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Effect of prolonged dehydration stress on the vector competence ofbioRxiv : the preprint server for biology · 2025
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christopher J HolmesDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0001-9612-366X
Elliott S BrownDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Dhriti SharmaDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Matthew WardenDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0001-9993-7976
Atit PathakDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Blaine PaytonDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Quynh NguyenDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Austin SpanglerDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Jaishna SivakumarDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Jacob M HendershotDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Joshua B BenoitDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.

Funding

Mosquito hydration status as a mechanism that alters pre-feeding host interactions and post-feeding physiologyR01AI148551 · NIAID · UNIVERSITY OF CINCINNATI · PI BENOIT, JOSH B., XIAO, YANYU · 2020 to 2024
$2.1M
NIAID NIH HHS R01 AI148551
6 · The paper itself

Abstract

The mosquito midgut is an important site for bloodmeal regulation while also acting as a primary site for pathogen exposure within the mosquito. Recent studies show that exposure to dehydrating conditions alters mosquito bloodfeeding behaviors as well as post-feeding regulation, likely altering how pathogens interact with the mosquito. Unfortunately, few studies have explored the underlying dynamics between dehydration and bloodmeal utilization, and the overall impact on disease transmission dynamics remains veiled. In this study, we find that dehydration-based feeding in the yellow fever mosquito,

Indexed as

Aedes aegyptiaquaporinbloodfeedingecdysteroid kinaseion transportosmolalitytranscriptomics

Identifiers

PMID36975959
PMCPMC10056721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.