Trial reportRadiology2023
CT-guided Pulsed Radiofrequency Combined with Steroid Injection for Sciatica from Herniated Disk: A Randomized Trial.
Open access · greenAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph
Trial report in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Intra-articular steroid injections for lumbar disk herniation: a systematic review and meta-analysis.Acta neurochirurgica · 2025Pooled it
- Injectable anti-inflammatory, antioxidant supramolecular nanofiber hydrogel for peripheral nerve injury repair and neuropathic pain relief.Materials today. Bio · 2026Article
- Improvement of occipital neuralgia by pulsed radiofrequency of the greater occipital nerve combined with local magnesium sulfate injection: a randomized controlled study.Frontiers in physiology · 2026Article
- Efficacy of Pulsed Radiofrequency Combination Therapy for Postherpetic Neuralgia: A Systematic Review and Bayesian Network Meta-Analysis.Journal of pain research · 2026Review
- Standalone ultrasound-based highly visualized volumetric spine imaging for surgical navigation.Scientific reports · 2025Article
- Modified transforaminal epidural steroid injection combined with pulsed radiofrequency: an effective treatment measure for lumbar radiculopathy.Frontiers in surgery · 2025Article
- Epidural steroid injections in lumbar disc herniation- Evidence synthesis from 72 randomised controlled trials (RCTs) and a total of 7701 patients.Brain & spine · 2025Article
- Efficacy and safety of pregabalin in the management of low back pain: a comprehensive meta-analysis.Frontiers in pharmacology · 2025Review
- Image-Guided Minimally Invasive Treatment Options for Degenerative Lumbar Spine Disease: A Practical Overview of Current Possibilities.Diagnostics (Basel, Switzerland) · 2024Review
- A new comprehensive MRI classification and grading system for lumbosacral central and lateral stenosis: clinical application and comparison with previous systems.La Radiologia medica · 2024Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
16 authors at 2 institutions in 2 countries.
Alessandro NapoliFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0001-8337-7652
Giulia AlfieriFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0001-9016-0574
Alessandro De MaioFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0003-3553-8671
Emanuela PanellaFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).
Roberto ScipioneFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0002-2321-6037
Giancarlo FacchiniFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).
Ugo AlbisinniFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0001-8108-0759
Paolo SpinnatoFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0001-6060-3215
Pier Giorgio NardisFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).
Roberto TramutoliFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0002-1656-8237
Jacopo LenziFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0001-5311-0834
Pejman GhanouniFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0002-6393-0964
Alberto BazzocchiFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).
Stefano PerottiFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).
Andrew J SchoenfeldFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0002-3691-1215
Carlo CatalanoFrom the Department of Radiological, Oncological, and Pathological Sciences, Policlinico Umberto I-Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy (A.N., G.A., A.D.M., R.S., P.G.N., S.P., C.C.); Spine Unit, Centro SaNa Servizi Sanitari Privati, Aprilia, Italy (A.N., E.P., R.S., R.T., J.L.); Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (G.F., U.A., P.S., A.B.); Department of Radiology, Stanford University, Stanford, Calif (P.G.); and Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.J.S.).ORCID 0000-0003-4208-9691
Policlinico Umberto I · ITBrigham and Women's Hospital · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Evidence regarding effective nonsurgical management of sciatica remains limited. Purpose To determine a difference in effectiveness between combined pulsed radiofrequency (PRF) and transforaminal epidural steroid injection (TFESI) treatment versus TFESI alone for sciatic pain due to lumbar disk herniation. Materials and Methods This prospective multicenter double-blind randomized clinical trial was conducted between February 2017 and September 2019 in participants with sciatica due to lumbar disk herniation lasting 12 weeks or longer that was not responsive to conservative treatment. Study participants were randomly assigned to undergo one CT-guided treatment with combined PRF and TFESI (
Indexed as
Intervertebral Disc DisplacementPulsed Radiofrequency TreatmentSciaticaHumansInjections, EpiduralMaleMiddle AgedPainProspective StudiesSteroidsTomography, X-Ray ComputedTreatment OutcomeSteroids
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.