Evidence map›Paper›PMID 36975733›Full record

ArticleHematology reports2023

Mutational Profile and Pathological Features of a Case of Interleukin-10 and RGS1-Positive Spindle Cell Variant Diffuse Large B-Cell Lymphoma.

Joaquim Carreras, Yara Yukie Kikuti, Masashi Miyaoka, Shinichiro Hiraiwa, Sakura Tomita, Haruka Ikoma, Yusuke Kondo, Atsushi Ito, Shunsuke Nagase, Hisanobu Miura and 5 more

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In one paragraph

Article in Hematology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Joaquim CarrerasDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.ORCID 0000-0002-6129-8299
Yara Yukie KikutiDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.ORCID 0000-0001-7013-3093
Masashi MiyaokaDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Shinichiro HiraiwaDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Sakura TomitaDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Haruka IkomaDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Yusuke KondoDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Atsushi ItoDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Shunsuke NagaseDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.ORCID 0000-0002-6130-3879
Hisanobu MiuraDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Giovanna RoncadorMonoclonal Antibodies Unit, Spanish National Cancer Research Center (Centro Nacional de Investigaciones Oncologicas, CNIO), Melchor Fernandez Almagro 3, 28029 Madrid, Spain.ORCID 0000-0002-9807-2875
Lluis ColomoDepartment of Pathology, Hospital del Mar, Passeig Maritim 25-29, 08003 Barcelona, Spain.ORCID 0000-0001-5236-5085
Rifat HamoudiDepartment of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-1402-0868
Elias CampoDepartment of Pathology, Hospital Clinic Barcelona, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Esther Koplowitz Center (CEK), Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), 08036 Barcelona, Spain.
Naoya NakamuraDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara 259-1193, Kanagawa, Japan.
Tokai University · JPCentro de Investigación Biomédica en Red de Cáncer · ESHospital Del Mar · ESSpanish National Cancer Research Centre · ESUniversity of Sharjah · AE

Funding

Al-Jalila Foundation AJF2018090Ministry of Education, Culture, Sports, Science and Technology 15K19061Ministry of Education, Culture, Sports, Science and Technology 18K15100Ministry of Education, Culture, Sports, Science and Technology 24590430Tokai University School of Medicine research incentive assistant plan 2021-B04University of Sharjah 22010902103
6 · The paper itself

Abstract

Diffuse large B-cell lymphoma with spindle cell morphology is a rare variant. We present the case of a 74-year-old male who initially presented with a right supraclavicular (lymph) node enlargement. Histological analysis showed a proliferation of spindle-shaped cells with narrow cytoplasms. An immunohistochemical panel was used to exclude other tumors, such as melanoma, carcinoma, and sarcoma. The lymphoma was characterized by a cell-of-origin subtype of germinal center B-cell-like (GCB) based on Hans' classifier (CD10-negative, BCL6-positive, and MUM1-negative); EBER negativity, and the absence of

Indexed as

diffuse large B-cell lymphomainterleukin 10LymphGen 1.0mutational profilingnext-generation sequencingregulator of G protein signaling 1spindle cell

Identifiers

PMID36975733
PMCPMC10048669
OpenAlexW4324045963

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read27
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.