Evidence map›Paper›PMID 36975685›Full record

ArticleGels (Basel, Switzerland)2023

Chain-Extendable Crosslinked Hydrogels Using Branching RAFT Modification.

Stephen Rimmer, Paul Spencer, Davide Nocita, John Sweeney, Marcus Harrison, Thomas Swift

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In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephen RimmerDepartment of Chemistry, University of Sheffield, Sheffield S10 2JA, UK.
Paul SpencerFaculty of Engineering, University of Bradford, Bradford BD7 1DP, UK.ORCID 0000-0003-0959-9008
Davide NocitaFaculty of Engineering, University of Bradford, Bradford BD7 1DP, UK.ORCID 0000-0002-0237-9881
John SweeneyFaculty of Engineering, University of Bradford, Bradford BD7 1DP, UK.
Marcus HarrisonDepartment of Chemistry, University of Sheffield, Sheffield S10 2JA, UK.
Thomas SwiftDepartment of Chemistry, University of Sheffield, Sheffield S10 2JA, UK.ORCID 0000-0002-8616-8458

Funding

Engineering and Physical Sciences Research Council EP/H501541/1Royal Society of Chemistry E21-83469525
6 · The paper itself

Abstract

Functional crosslinked hydrogels were prepared from 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA). The acid monomer was incorporated both via copolymerization and chain extension of a branching, reversible addition-fragmentation chain-transfer agent incorporated into the crosslinked polymer gel. The hydrogels were intolerant to high levels of acidic copolymerization as the acrylic acid weakened the ethylene glycol dimethacrylate (EGDMA) crosslinked network. Hydrogels made from HEMA, EGDMA and a branching RAFT agent provide the network with loose-chain end functionality that can be retained for subsequent chain extension. Traditional methods of surface functionalization have the downside of potentially creating a high volume of homopolymerization in the solution. Branching RAFT comonomers act as versatile anchor sites by which additional polymerization chain extension reactions can be carried out. Acrylic acid grafted onto HEMA-EGDMA hydrogels showed higher mechanical strength than the equivalent statistical copolymer networks and was shown to have functionality as an electrostatic binder of cationic flocculants.

Indexed as

chain extensiongraftingHEMAhydrogelmodificationpoly(acrylic acid)

Identifiers

PMID36975685
PMCPMC10048396

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.