Evidence map›Paper›PMID 36975597›Full record

ArticleDiseases (Basel, Switzerland)2023

Promising Antimicrobial Action of Sustained Released Curcumin-Loaded Silica Nanoparticles against Clinically Isolated

Adileh Shirmohammadi, Solmaz Maleki Dizaj, Simin Sharifi, Shirin Fattahi, Ramin Negahdari, Mohammad Ali Ghavimi, Mohammad Yousef Memar

Open access · goldFull text read
In one paragraph

Article in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. The Impact of Scaling and Root Planing onArchives of Razi Institute · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Silica nanoparticles in medicine: overcoming pathologies through advanced drug delivery, diagnostics, and therapeutic strategies.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adileh ShirmohammadiDepartment of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 5166, Iran.
Solmaz Maleki DizajDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 5166, Iran.ORCID 0000-0003-4759-7222
Simin SharifiDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 5166, Iran.ORCID 0000-0002-3020-3779
Shirin FattahiDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 5166, Iran.
Ramin NegahdariDepartment of Prosthodontics, Faculty of Dentistry, Tabriz University of Medical Science, Tabriz 5166, Iran.
Mohammad Ali GhavimiDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 5166, Iran.
Mohammad Yousef MemarInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 5166, Iran.
Tabriz University of Medical Sciences · IRUniversity of Tabriz · IR

Funding

Tabriz University of Medical Sciences 61957
6 · The paper itself

Abstract

background

methodsCurcumin-loaded silica nanoparticles were prepared using the chemical precipitation method and then were characterized using conventional methods (properties such as the particle size, drug loading percentage, and release pattern).

resultsThe curcumin-loaded silica nanoparticles showed a nanometric size and a drug loading percentage of 68% for curcumin. The nanoparticles had a mesoporous structure and rod-shaped morphology. They showed a relatively rapid release pattern in the first 5 days. The release of the drug from the nanoparticles continued slowly until the 45th day. The results of

conclusionBased on the obtained results, it can be concluded that the local nanocurcumin application for periodontal disease and implant-related infections can be considered a promising method for the near future in dentistry.

Indexed as

antimicrobial actioncurcumin-silica nanoparticlesperiodontal diseasesPorphyromonas gingivalissustained release

Identifiers

PMID36975597
PMCPMC10047251
OpenAlexW4323663260

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.