ReviewDentistry journal2023
Bioactive Materials for Caries Management: A Literature Review.
Review in Dentistry journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 52 citations in OpenAlex.
- Effectiveness of Bioactive Glass-Based Toothpaste for Early Childhood Caries Prevention: A Randomized Controlled Trial.International dental journal · 2026Trial
- Clinical performance of a glass-hybrid system in comparison with a resin composite in two-surface class II restorations: a 5-year randomised multi-centre study.Clinical oral investigations · 2024Trial
- Recent Advances in Caries Prevention and Non-Invasive Management: From Ecological Modulation to Precision Interventions.Dentistry journal · 2026Review
- Effects of Bleaching Protocols on the Esthetic Outcome and Surface Integrity of Enamel Treated With an Ammonia-Free Silver Fluoride Solution.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Effect of immediate and delayed composite restoration on shear bond strength to remineralized initial enamel lesions: an in vitro study.The Saudi dental journal · 2026Article
- Effect of Nano-Silver Fluoride Containing 2000 ppm Silver Nanoparticles on the Microhardness and Color of Flowable Resin Composites: An In Vitro Pilot Study.Materials (Basel, Switzerland) · 2026Article
- Determination of the Properties of an Experimental Dental Composite with Addition of Hydroxyapatite with Varied Micro and Nano Particle Size: An Evaluation of Mechanical Properties, Ion Release, and Surface Characteristics.Journal of functional biomaterials · 2026Article
- Bridging the Gap Between Knowledge and Practice: Contemporary Preventive Strategies in Modern Dental Care-A Cross-Sectional Survey of Practicing Dentists.Journal of clinical medicine · 2026Article
- Effectiveness of Tooth-colored Restorative Materials in Masking Discoloration Caused by Silver Diamine Fluoride: A Systematic Review ofInternational journal of clinical pediatric dentistry · 2026Review
- Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026Review
- Regenerative Strategies in Pediatric Dentistry: A Comprehensive Overview of Tissue Engineering from Past to Future.Advances in experimental medicine and biology · 2026Review
- Review
- Evaluation of Factors Affecting Fluoride Release from Dental Sealants: A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- Two-Year Bonding Performances of a Universal Adhesive After Dentin Pre-Treatment With Two-Step Silver-Containing Solutions.The journal of adhesive dentistry · 2025Article
- Minimally Invasive Techniques for Managing Dental Caries in Children: Efficacy, Applications, and Future Directions.Cureus · 2025Review
- Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation.Dentistry journal · 2025Article
- Advanced Lasers and Their Applications in Dentistry.Dentistry journal · 2025Review
- An in vitro study of fluoride-preloaded halloysite nanotubes to enhance the fluoride release in conventional and resin-modified glass ionomer cements.The Saudi dental journal · 2024Article
- Synthesis and Application of Silver Nanoparticles for Caries Management: A Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Hybrid Hydroxyapatite-Metal Complex Materials Derived from Amino Acids and Nucleobases.Molecules (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Researchers have developed novel bioactive materials for caries management. Many clinicians also favour these materials, which fit their contemporary practice philosophy of using the medical model of caries management and minimally invasive dentistry. Although there is no consensus on the definition of bioactive materials, bioactive materials in cariology are generally considered to be those that can form hydroxyapatite crystals on the tooth surface. Common bioactive materials include fluoride-based materials, calcium- and phosphate-based materials, graphene-based materials, metal and metal-oxide nanomaterials and peptide-based materials. Silver diamine fluoride (SDF) is a fluoride-based material containing silver; silver is antibacterial and fluoride promotes remineralisation. Casein phosphopeptide-amorphous calcium phosphate is a calcium- and phosphate-based material that can be added to toothpaste and chewing gum for caries prevention. Researchers use graphene-based materials and metal or metal-oxide nanomaterials as anticaries agents. Graphene-based materials, such as graphene oxide-silver, have antibacterial and mineralising properties. Metal and metal-oxide nanomaterials, such as silver and copper oxide, are antimicrobial. Incorporating mineralising materials could introduce remineralising properties to metallic nanoparticles. Researchers have also developed antimicrobial peptides with mineralising properties for caries prevention. The purpose of this literature review is to provide an overview of current bioactive materials for caries management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.