Evidence map›Paper›PMID 36975528›Full record

ArticleCurrent issues in molecular biology2023

Increased Yield of Extracellular Vesicles after Cytochalasin B Treatment and Vortexing.

Sirina V Kurbangaleeva, Valeriia Y Syromiatnikova, Angelina E Prokopeva, Aleksey M Rogov, Artur A Khannanov, Albert A Rizvanov, Marina O Gomzikova

Open access · goldFull text read
In one paragraph

Article in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sirina V KurbangaleevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.ORCID 0000-0003-1637-1888
Valeriia Y SyromiatnikovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
Angelina E ProkopevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
Aleksey M RogovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
Artur A KhannanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.ORCID 0000-0001-5119-8449
Albert A RizvanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.ORCID 0000-0002-9427-5739
Marina O GomzikovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.ORCID 0000-0002-0826-7370
Kazan Federal University · RU

Funding

Russian Government Program "Recruitment of the Leading Scientists into the Russian Institutions of Higher Education" №075-15-2021-600Russian Science Foundation №21-75-10035
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are promising therapeutic instruments and vectors for therapeutics delivery. In order to increase the yield of EVs, a method of inducing EVs release using cytochalasin B is being actively developed. In this work, we compared the yield of naturally occurring extracellular vesicles and cytochalasin B-induced membrane vesicles (CIMVs) from mesenchymal stem cells (MSCs). In order to maintain accuracy in the comparative analysis, the same culture was used for the isolation of EVs and CIMVs: conditioned medium was used for EVs isolation and cells were harvested for CIMVs production. The pellets obtained after centrifugation 2300×

Indexed as

cytochalasin B-induced membrane vesiclesdelivery systemextracellular vesiclesmesenchymal stem cells

Identifiers

PMID36975528
PMCPMC10047179
OpenAlexW4327620994

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read45
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.