ReviewBiomimetics (Basel, Switzerland)2023
Bone Apatite Nanocrystal: Crystalline Structure, Chemical Composition, and Architecture.
Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Injectable hydrogels for bone regeneration: from materials design to clinical translation.RSC advances · 2026Review
- Innovative Hydroxyapatite-Hydrogel Composites for Cartilage Regeneration.Gels (Basel, Switzerland) · 2026Review
- Hydroxyapatite-Polysaccharide Composites Synthesized from Maize Lime-Cooking Wastewater for Bone Tissue Engineering.Journal of functional biomaterials · 2026Article
- Strontium-substituted hydroxyapatite nanoparticles as dual-function regulators of osteoblast mineralization and RANKL-induced osteoclastogenesis.Journal of materials science. Materials in medicine · 2026Article
- Protein adsorption at material interface: mechanistic design framework for engineering ceramic scaffolds for bone repair applications.Biomedical engineering online · 2026Review
- Article
- Effects of HCl concentration and immersion time on physicochemical properties, BMP-2 detection, degradation, and osteoblast response of human demineralized tooth matrix.Biomaterial investigations in dentistry · 2026Article
- Modulating the crystallinity of biphasic calcium phosphate composites balances surface and ionic cues to enhance osteogenesis via integrin-mediated cytoskeletal signaling.Materials today. Bio · 2025Article
- New NaBMC chemistry · 2025Article
- Comparative Chemical and Physical Characterization of Biomimetic Versus Commercial Hydroxyapatites for Tooth Enamel Repair.Biomimetics (Basel, Switzerland) · 2025Article
- Influence of calcination temperature on equine bone hydroxyapatite structure and lead adsorption efficiency.Scientific reports · 2025Article
- Article
- Anisotropy visualisation from X-ray diffraction of biological apatite in mixed phase calcified tissue samples.Scientific reports · 2025Article
- Article
- Revisiting Physicochemical and Biological Properties of ZnNanotechnology, science and applications · 2025Article
- Evaluation of the In Vitro Behavior of Electrochemically Deposited Plate-like Crystal Hydroxyapatite Coatings.Biomimetics (Basel, Switzerland) · 2024Article
- The location of cationic substitutions in carbonated biomimetic apatites significantly affects crystal nanomechanics.Scientific reports · 2024Article
- Evaluating various properties of nanohydroxyapatite synthesized from eggshells and dual-doped with SiHeliyon · 2024Article
- Silver phosphate-modified carbonate apatite honeycomb scaffolds for anti-infective and pigmentation-free bone tissue engineering.Materials today. Bio · 2024Article
- Inorganic Pyrophosphate at Serum Concentration May Not Be Able to Inhibit Mineralization: A Study in Aqueous Solutions and Serum.ACS omega · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The biological and mechanical functions of bone rely critically on the inorganic constituent, which can be termed as bone apatite nanocrystal. It features a hydroxylapatite-like crystalline structure, complex chemical compositions (e.g., carbonate-containing and calcium- and hydroxyl-deficient), and fine geometries and properties. The long research with vast literature across broad spectra of disciplines and fields from chemistry, crystallography, and mineralogy, to biology, medical sciences, materials sciences, mechanics, and engineering has produced a wealth of knowledge on the bone apatite nanocrystal. This has generated significant impacts on bioengineering and industrial engineering, e.g., in developing new biomaterials with superior osteo-inductivities and in inspiring novel strong and tough composites, respectively. Meanwhile, confusing and inconsistent understandings on the bone mineral constituent should be addressed to facilitate further multidisciplinary progress. In this review, we present a mineralogical account of the bone-related ideal apatite mineral and then a brief historical overview of bone mineral research. These pave the road to understanding the bone apatite nanocrystal via a material approach encompassing crystalline structure, diverse chemical formulae, and interesting architecture and properties, from which several intriguing research questions emerge for further explorations. Through providing the classical and latest findings with decent clearness and adequate breadth, this review endeavors to promote research advances in a variety of related science and engineering fields.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.