ArticleJournal of the American Heart Association2023
Stage 1 Hypertension and the 10-Year and Lifetime Risk of Cardiovascular Disease: A Prospective Real-World Study.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Three-Year Durability of Radiofrequency Renal Denervation: SPYRAL HTN-ON MED.Journal of the American Heart Association · 2026Trial
- Hidden morbidity in early adulthood: Discrepancies between self-reported and screening-detected health conditions among university students in Ghana.Global epidemiology · 2026Article
- Association between hypertension and incidence of cardiovascular disease events in young adults with type 2 diabetes: a nationwide cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Evaluating the Attenuation of Black-White Disparities in Cardiovascular Disease Incidence and Total Mortality by Life's Essential 8.Circulation. Population health and outcomes · 2026Article
- Interrelationships Between Key Cardiovascular Risk Factors, Chronic Kidney Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease.Current cardiology reports · 2026Review
- Serum potassium and sodium levels and nutrient intake in population exposed to radiation from the Semipalatinsk nuclear test site.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Association of supine versus seated hypertension with cardiovascular events in older adults.European geriatric medicine · 2026Article
- Adverse childhood experiences and hypertension jointly increase cardiovascular risk: evidence from three national aging cohorts.BMC public health · 2026Article
- Updates in the 2025 AHA/ACC Hypertension Guideline.Current hypertension reports · 2026Review
- Joint associations between exercising and classical cardiometabolic risk factors with all-cause, premature and cardiovascular mortality: a prospective cohort study among Mexican adults.Frontiers in endocrinology · 2026Article
- Implications of the 2025 AHA/ACC hypertension guideline on hypertension prevalence, treatment eligibility and blood pressure control in Nigeria: a cross-sectional comparative study.BMJ public health · 2026Article
- Associations of relative muscular strength with blood pressure changes and incident hypertension: a prospective cohort study in Korea.BMC public health · 2025Article
- Association between cardiovascular-kidney-metabolic health metrics and long-term cardiovascular risk: Findings from the Chinese Multi-provincial Cohort Study.Chinese medical journal · 2025Article
- The association between cystatin C and hypertension risk in diabetes patients: A multi-cohort cross-sectional study.iScience · 2025Article
- Beyond the Tip of the Iceberg: Rethinking Hypertension Screening in Young Adults.Journal of the American Heart Association · 2025Article
- Prevalence of Hypertension in the Late Postpartum Period by Hypertensive Status in Pregnancy.O&G open · 2025Article
- Prerequisites for Cost-Effective Home Blood Pressure Telemonitoring: Early Health Economic Analysis.JMIR cardio · 2025Article
- Association between physical activity behaviors and hypertension with comorbid multiple chronic diseases in South Korean middle-aged and elderly: an analysis based on association rule.BMC public health · 2025Article
- Definitions of chronic disease need to be more patient centred.BMJ (Clinical research ed.) · 2024Article
- Cost-effectiveness of treatment in adults with blood pressure of 130-139/80-89 mmHg and high cardiovascular risk in China: a modelling study.The Lancet regional health. Western Pacific · 2024Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
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Abstract
Background The 10-year and lifetime cardiovascular disease risk in the population with stage 1 hypertension and the effects of recovery from and progression of stage 1 hypertension remain undetermined. Methods and Results This prospective cohort study included 96 268 individuals with blood pressure measurements obtained in 2006 and again in 2010. The 10-year cardiovascular disease risk was estimated using the multivariable Cox proportional hazards model, and the lifetime risk was calculated using a modified survival analysis that accounted for the competing risk of death. Stage 1 hypertension was detected in 30.83% of the cohort. The 10-year cardiovascular disease risk was 2.80%, and the lifetime risk was 16.61%. Compared with the normal blood pressure group, the stage 1 hypertension group had a 35% higher 10-year risk (hazard ratio [HR], 1.35 [95% CI, 1.19-1.52]) and a 36% higher lifetime risk (HR, 1.36 [95% CI, 1.25-1.49]). By 2010, 12.57% of the participants with stage 1 hypertension had progressed to stage 2, with a significant 156% increase in 10-year risk (HR, 2.56 [95% CI, 2.11-3.11]) and an increased lifetime risk of 129% (HR, 2.29 [95% CI, 1.89-2.77]). There was no appreciable change in risk in those with stage 1 hypertension whose blood pressure returned to the normal-elevated range. Conclusions Stage 1 hypertension was associated with a significant increase in 10-year and lifetime cardiovascular disease risk. Progression to stage 2 hypertension was associated with a marked increase in lifetime risk. The current guidelines require revision to promote early detection and appropriate management of blood pressure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.