Evidence map›Paper›PMID 36974761›Full record

ArticleJournal of the American Heart Association2023

Prognostic Value of Machine-Learning-Based PRAISE Score for Ischemic and Bleeding Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

Boqun Shi, Hao-Yu Wang, Jinpeng Liu, Zhongxing Cai, Chenxi Song, Dong Yin, Hongjian Wang, Qiuting Dong, Weihua Song, Ke-Fei Dou

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Boqun ShiCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.ORCID 0000-0002-3403-9128
Hao-Yu WangCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.ORCID 0000-0002-5634-0966
Jinpeng LiuCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.
Zhongxing CaiCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.
Chenxi SongCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.
Dong YinCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.
Hongjian WangCoronary Heart Disease Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.ORCID 0000-0002-9956-7511
Qiuting DongCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.
Weihua SongCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.ORCID 0000-0001-9358-5826
Ke-Fei DouCardiometabolic Medicine Center, Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China.ORCID 0000-0002-8372-6338
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The PRAISE (Prediction of Adverse Events Following an Acute Coronary Syndrome) score is a machine-learning-based model for predicting 1-year all-cause death, myocardial infarction, and Bleeding Academic Research Consortium (BARC) type 3/5 bleeding. Its utility in an unselected Asian population undergoing percutaneous coronary intervention for acute coronary syndrome remains unknown. We aimed to validate the PRAISE score in a real-world Asian population. Methods and Results A total of 6412 consecutive patients undergoing percutaneous coronary intervention for acute coronary syndrome were prospectively included. The PRAISE scores were compared with established scoring systems (GRACE [Global Registry of Acute Coronary Events] 2.0, PRECISE-DAPT (Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy), and PARIS [Patterns of Non-Adherence to Anti-Platelet Regimen in Stented Patients]) to evaluate their discrimination, calibration, and reclassification. The risk of all-cause mortality (hazard ratio [HR], 12.24 [95% CI, 5.32-28.15]) and recurrent acute myocardial infarction (HR, 3.92 [95% CI, 1.76-8.73]) was greater in the high-risk group than in the low-risk group. The C-statistics for death, myocardial infarction, and major bleeding were 0.75 (0.67-0.83), 0.61 (0.52-0.69), and 0.62 (0.46-0.77), respectively. The observed to expected ratio of death, myocardial infarction, and major bleeding was 0.427, 0.260, and 0.106, respectively. Based on the decision curve analysis, the PRAISE score displayed a slightly greater net benefit for the 1-year risk of death (5%-10%) than the GRACE score did. Conclusions The PRAISE score showed limited potential for risk prediction in our validation cohort with acute coronary syndrome. As a result, new prediction models or model refitting are required with improved discrimination and accuracy in risk prediction.

Indexed as

Acute Coronary SyndromeMyocardial InfarctionPercutaneous Coronary InterventionDrug Therapy, CombinationHemorrhageHumansIschemiaPlatelet Aggregation InhibitorsPrognosisRisk AssessmentTreatment OutcomePlatelet Aggregation Inhibitorsacute coronary syndromemachine learningPRAISE scorerisk stratification

Identifiers

PMID36974761
PMCPMC10122888
OpenAlexW4361190650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.