SynthesisAsian Pacific journal of cancer prevention : APJCP2023
Prevalence and Impact of Fatigue on Quality of Life (QOL) of Cancer Patients Undergoing Chemotherapy: A Systematic Review and Meta-Analysis.
Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Efficacy and Safety of Neoadjuvant Chemotherapy Plus Concurrent Chemoradiotherapy Compared to Concurrent Chemoradiotherapy Alone in Locally Advanced Cervical Cancer: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- Safety and Efficacy of Bispecific Antibodies in Adults with Large B-Cell Lymphomas: A Systematic Review of Clinical Trial Data.International journal of molecular sciences · 2024Pooled it
- Performance of EQ5D-5L and AHPEQS for measuring outcomes and experiences of patients with peripherally inserted central catheters: a secondary analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Trial
- Impact of continuous care based on multidisciplinary collaboration on the quality of life of patients with colorectal cancer undergoing chemotherapy.Frontiers in medicine · 2026Trial
- A study on improving cancer-related fatigue and disease-related psychological variables in patients with cervical cancer based on online mindfulness-based stress reduction: a randomized controlled trial.BMC women's health · 2024Trial
- Impact of radiotherapy on quality of life reported by elderly patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Suicide Risk and Associated Factors in Patients with Pancreatic Cancer: A Systematic Review.Diseases (Basel, Switzerland) · 2026Review
- Tendencies in the association between fatigue and quality of life in terminally ill patients with cancer admitted to a palliative care unit.Palliative & supportive care · 2026Article
- Effects of chemotherapy on cognitive and physical effort-based decision-making tasks in rats.Psychopharmacology · 2026Article
- Effects of Sitting Baduanjin on Cancer-Related Fatigue in Patients With Advanced Cancer: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Effects of Multicomponent Versus Aerobic Training on Body Composition, Physical Fitness, Psychological Health, and Quality of Life in Cancer Survivors: A 24-Week Randomized Controlled Trial.Sports (Basel, Switzerland) · 2026Article
- Article
- A mixed-methods study of how cancer-related fatigue affects occupational participation and engagement, and is managed in daily life.The British journal of occupational therapy · 2026Article
- A prospective longitudinal study of the changes in multidimensional fatigue and its associated factors in patients undergoing brachytherapy for cervical cancer.Scientific reports · 2025Article
- Association of quality of life in older patients with breast cancer: a cross-sectional study from China.BMJ open · 2025Observational
- Symptom clusters and impact on quality of life in lung cancer patients undergoing chemotherapy.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Win Statistics in Observational Cancer Research: Integrating Clinical and Quality-of-Life Outcomes.Journal of clinical medicine · 2024Article
- The Influence of Sociodemographic Factors and Clinical Aspects on the Quality of Life of Surgically Treated Patients with Colorectal Cancer.Cancer management and research · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFatigue is a typical consequence of cancer that can affect one's quality of life (QOL). The goal of this review is to provide comprehensive data on the impact of fatigue on QOL of cancer patients.
methodsAn electronic data search in Web of Science, SCOPUS, and PubMed for relevant papers; those written in English; those reporting quantitative data; and those including more than one hundred patients who received just chemotherapy were included. Studies involving participants that received other kinds of anti-neoplastic therapies were excluded.
resultsA total of 35 papers published between January 2000 and December 2021 were retrieved from the search databases of which (11612 patients) met the inclusion criteria. Findings showed that fatigue negatively affected QOL with a pooled prevalence of 49% (95% CI; 25.00-74.00) and the significant heterogeneity between articles was (I²=98%, P <0.001). Further, breast cancer contributed to the majority of selected articles with about 55 % (95%CI; 9:00- 94:00), followed by cancer (unspecified) 44% (95%CI; 5:00 - 92:00). Most studies (71%) (95%CI; 4:00 - 99:00) used the brief fatigue inventory (BFI) tool to assess severity of fatigue and 39% (95%CI; 17:00 -68:00) employed the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire to evaluate QOL among cancer survivors.
conclusionThe prevalence of fatigue in cancer patients is high and fatigue has a negative impact on QOL of cancer patients receiving chemotherapy. Directionality, fatigue needs to be addressed and treated properly for better improvement of health status and QOL in cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.