ArticleBrain and behavior2023
Long-term effects of childhood trauma subtypes on adult brain function.
Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- Anxiety as a Mediator Between Childhood Trauma and Social Competence Among Adolescents and Young Adults.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2026Article
- Association of life-course stressful life events with later-life intrinsic capacity: A multi-cohort study.The journal of nutrition, health & aging · 2026Article
- Trauma-informed practice for children and young people with intellectual disabilities: A scoping review.The British journal of educational psychology · 2026Article
- How Childhood Maltreatment Contributes to Explaining Depressive Symptoms in Transgender and Gender-Diverse Individuals.Healthcare (Basel, Switzerland) · 2026Article
- Childhood trauma and anxiety symptoms among Chinese university students: the moderating and mediating roles of mindfulness.BMC psychology · 2026Article
- Neural Correlates of Social Exclusion and Childhood Trauma in Borderline Personality Disorder.Cureus · 2025Article
- From triple-mode network to triple-layered model - novel insights in social cognition.Indian journal of psychiatry · 2025Article
- Pathways from parental trauma exposure to Syrian and Iraqi refugee youth mental health symptoms: a multi-level mediation analysis.BMC public health · 2025Article
- Childhood Trauma andmedRxiv : the preprint server for health sciences · 2025Article
- Childhood Maltreatment Associated with Anxiety and Depression and Complex PTSD Symptoms.Psychiatry and clinical psychopharmacology · 2024Article
- Alterations in the white matter structure of major depressive disorder patients and their link to childhood trauma.Frontiers in psychiatry · 2024Article
- Effect of Adverse Childhood Experiences, Parenting Styles, and Family Accommodation on Patients Diagnosed with Obsessive-Compulsive Disorder.Alpha psychiatry · 2023Article
- Long-term effects of childhood trauma subtypes on adult brain function.Brain and behavior · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChildhood trauma is prevalent in our society, whereas little is known about why and how different forms of early traumatic experiences exert long-term effects on differential brain function in adulthood. PURPOSE: This study aimed to scale experience-specific neural correlates of distinct subtypes of childhood trauma.
methodsWe used resting-state functional magnetic resonance imaging data from 216 adults with different degrees of childhood trauma. Graph analysis was combined with the Childhood Trauma Questionnaire to inspect the impact of distinct subtypes of childhood trauma on the brain.
resultsWe found that childhood trauma experiences have a detrimental effect on depression and anxiety behavior. On one hand, childhood neglect scores were positively associated with network transmission efficiency of regions involved in cognitive and executive functions, such as temporal lobe, insular cortex, and parahippocampal gyrus. On the other hand, childhood abuse scores were tightly linked to functional reorganizations of regions mediated by immature ego defense system and damaged emotion representation. Specifically, the abuse scores were positively associated with network transmission efficiency of the visual, auditory, linguistic, and motor cortex. Isolated communications in temporal cortex and supplementary motor cortex were related to emotional and physical abuse scores.
conclusionsOur data showed the differential associations of abusive and neglectful experiences with brain function in adulthood. These experience-specific associations could underpin potentially differential risks of specific forms of psychiatric sequelae in adulthood. More attentions to maltreated children and timely psychological treatment are needed to reduce the incidence of psychosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.