Evidence map›Paper›PMID 36974036›Full record

ReviewOrthopedic research and reviews2023

Risks in the Management of Polytrauma Patients: Clinical Insights.

Karthikeyan P Iyengar, Aakaash S Venkatesan, Vijay K Jain, Madapura K Shashidhara, Husam Elbana, Rajesh Botchu

Registry-linked trialAbstract readReview
In one paragraph

Review in Orthopedic research and reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06050759 (C-Reactive Protein / Albumin Ratio as a Predictive Inflammatory Marker for Postoperative Systemic Inflammatory Response Syndrome and/or Sepsis in Polytraumatized Patients in ICU), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06050759 completednot on this map

C-Reactive Protein / Albumin Ratio as a Predictive Inflammatory Marker for Postoperative Systemic Inflammatory Response Syndrome and/or Sepsis in Polytraumatized Patients in ICU

TypeobservationalSponsorAin Shams UniversityRan2023 to 2024Enrolled100ConditionsCrpArmsCRP and Albumin level in blood sample
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of osteosynthesis of the bony thorax in the context of polytrauma compared to conservative treatment: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Association between sustained moderate hyperglycemia within first 48 hours and poor functional outcome after polytrauma: A retrospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Patterns of sex-specific outcomes and mortality in polytrauma: a demographic and epidemiologic analysis by injury severity score.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Observational
  13. Review
  14. The NACA score predicts mortality in polytrauma patients before hospital admission: a registry-based study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karthikeyan P IyengarDepartment of Orthopaedics, Southport and Ormskirk NHS Trust, Southport, UK.ORCID 0000-0002-4379-1266
Aakaash S VenkatesanDepartment of Orthopaedics, University Hospital Sussex, Worthing, UK.
Vijay K JainDepartment of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Madapura K ShashidharaDepartment of Anesthesiology, Stockport NHS Foundation NHS Trust, Stockport, UK.
Husam ElbanaDepartment of Orthopaedics, Royal Lancaster Infirmary, Lancaster, UK.
Rajesh BotchuDepartment of Musculoskeletal Radiology, Royal Orthopaedic Hospital, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polytrauma, a patient's condition with multiple injuries that involve multiple organs or systems, is the leading cause of mortality in young adults. Trauma-related injuries are a major public health concern due to their associated morbidity, high disability, associated death, and socioeconomic consequences. Management of polytrauma patients has evolved over the last few decades due to the development of trauma systems, improved pre-hospital assessment, transport and in-hospital care supported by complementary investigations. Recognising the mortality patterns in trauma has led to significant changes in the approach to managing these patients. A structured approach with application of advanced trauma life support (ATLS) algorithms and optimisation of care based on clinical and physiological parameters has led to the development of early appropriate care (EAC) guidelines to treat these patients, with subsequent improved outcomes in such patients. The journey of a polytrauma patient through the stages of pre-hospital care, emergency resuscitation, in-hospital stabilization and rehabilitation pathway can be associated with risks at any of these phases. We describe the various risks that can be anticipated during the management of polytrauma patients at different stages and provide clinical insights into early recognition and effective treatment of these to improve clinical outcomes.

Indexed as

abbreviated injury scaleearly appropriate carepolytraumaresuscitationshocktrauma related coagulopathy

Identifiers

PMID36974036
PMCPMC10039633

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.