ArticleBMC geriatrics2023
Association between multimorbidity patterns and incident depression among older adults in Taiwan: the role of social participation.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Multimorbidity and the risk of depression: a systematic review of cohort studies.Journal of global health · 2026Pooled it
- Multimorbidity patterns and mental health in late life: a systematic review of longitudinal studies.European geriatric medicine · 2026Pooled it
- The prevalence of disability in older adults with multimorbidity: a meta-analysis.Aging clinical and experimental research · 2024Pooled it
- The bidirectional relationships among multimorbidity, depression, and catastrophic health expenditures in middle-aged and older Chinese adults: random-intercept, cross-lagged panel model.BMC public health · 2026Article
- Multimorbidity and functioning disparities in retired older adults: longitudinal trajectories, disease clusters, and mediating mechanisms.BMC geriatrics · 2026Article
- Article
- Experiences of Social Relationships for Adults Living With Multiple Long-Term Conditions: A Qualitative Interview Study.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Social participation and insomnia in Chinese older adults with multimorbidity: mediating roles of frailty, anxiety, and depression.BMC geriatrics · 2025Article
- Cluster and survival analysis of UK biobank data reveals associations between physical multimorbidity clusters and subsequent depression.Communications medicine · 2025Article
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5 authors.
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Abstract
backgroundPrevious research has found different multimorbidity patterns that negatively affects health outcomes of older adults. However, there is scarce evidence, especially on the role of social participation in the association between multimorbidity patterns and depression. Our study aimed to explore the relationship between multimorbidity patterns and depression among older adults in Taiwan, including the social participation effect on the different multimorbidity patterns.
methodsData were retracted from the Taiwan longitudinal study on ageing (TLSA) for this population-based cohort study. 1,975 older adults (age > 50) were included and were followed up from 1996 to 2011. We used latent class analysis to determine participants' multimorbidity patterns in 1996, whereas their incident depression was determined in 2011 by CES-D. Multivariable logistic regression was used to analyse the relationship between multimorbidity patterns and depression.
resultsThe participants' average age was 62.1 years in 1996. Four multimorbidity patterns were discovered through latent class analysis, as follows: (1) Cardiometabolic group (n = 93), (2) Arthritis-cataract group (n = 105), (3) Multimorbidity group (n = 128) and (4) Relatively healthy group (n = 1649). Greater risk of incident depression was found among participants in the Multimorbidity group (OR: 1.62; 95% CI: 1.02-2.58) than the Relatively healthy group after the multivariable analysis. Compare to participants in the relatively healthy group with social participation, participants in the arthritis-cataract group without social participation (OR: 2.22, 95% CI: 1.03-4.78) and the multimorbidity group without social participation (OR: 2.21, 95% CI: 1.14-4.30) had significantly increased risk of having depression.
conclusionDistinct multimorbidity patterns among older adults in Taiwan are linked with the incident depression during later life, and social participation functioned as a protective factor.
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