ArticleBMC genomics2023
Comparative metabolomics of root-tips reveals distinct metabolic pathways conferring drought tolerance in contrasting genotypes of rice.
Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 47 citations in OpenAlex.
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- Tissue-specific metabolomic profiling reveals cultivar-dependent drought tolerance mechanisms in rice (Oryza sativa L.).BMC plant biology · 2026Article
- A plastidic starch biosynthetic pathway defines columella-specific carbon metabolism in rice root tips.Frontiers in plant science · 2026Article
- Metabolic response strategies of spring wheat under osmotic stress.Frontiers in plant science · 2026Article
- Integrative comparative proteomics identifies core differentially expressed proteins and pathways for drought tolerance by exploiting contrasting rice varieties.Frontiers in plant science · 2026Article
- Hydrogen sulfide alleviates thiocyanate stress in rice seedlings via tissue-specific carbon and nitrogen metabolic reprogramming.Frontiers in plant science · 2026Article
- Responses and adaptations of plants to abiotic stress: transcriptional regulation of secondary metabolic pathways, metabolomics, and nanobiological approaches.Frontiers in genetics · 2026Review
- Progress and Impacts of "Omics" Technologies in Understanding the Drought Response in Cassava: Adoption for Food Security in Africa.Plant-environment interactions (Hoboken, N.J.) · 2025Review
- An Integrated Meta-QTL and Transcriptome Analysis Provides Candidate Genes Associated with Drought Tolerance in Rice Seedlings.Plants (Basel, Switzerland) · 2025Article
- Drought-Driven Rhizosphere Microbiome and Metabolome Remodeling in Wild vs. CultivatedPlants (Basel, Switzerland) · 2025Article
- Zinc biofortification and yield enhancement in rice with nano- primed seeds and foliar sprays.Scientific reports · 2025Article
- Innovative metabolic reprogramming in rice: unlocking drought resilience through microbial consortia interaction and sustainable agriculture.3 Biotech · 2025Review
- Integrating metabolomics and high-throughput phenotyping to elucidate metabolic and phenotypic responses to early-season drought stress in Nordic spring wheat.BMC plant biology · 2025Article
- Genome-wide identification, evolution, and expression and metabolic regulation of the maize CHS gene family under abiotic stress.BMC genomics · 2025Article
- Identification of critical transition signal (CTS) to characterize regulated stochasticity during ABA-induced growth-to-defense transition.BMC plant biology · 2025Article
- Deciphering nutrient stress in plants: integrative insight from metabolomics and proteomics.Functional & integrative genomics · 2025Review
- Metabolite Profiling of the Resurrection GrassPlants (Basel, Switzerland) · 2025Article
- Whole Genome Identification and Integrated Analysis of Long Non-Coding RNAs Responding ABA-Mediated Drought Stress inCurrent issues in molecular biology · 2024Article
- Transcriptomic and Metabolomic Profiling of Root Tissue in Drought-Tolerant and Drought-Susceptible Wheat Genotypes in Response to Water Stress.International journal of molecular sciences · 2024Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe mechanisms underlying rice root responses to drought during the early developmental stages are yet unknown.
resultsThis study aimed to determine metabolic differences in IR64, a shallow-rooting, drought-susceptible genotype, and Azucena, a drought-tolerant and deep-rooting genotype under drought stress. The morphological evaluation revealed that Azucena might evade water stress by increasing the lateral root system growth, the root surface area, and length to access water. At the same time, IR64 may rely mainly on cell wall thickening to tolerate stress. Furthermore, significant differences were observed in 49 metabolites in IR64 and 80 metabolites in Azucena, for which most metabolites were implicated in secondary metabolism, amino acid metabolism, nucleotide acid metabolism and sugar and sugar alcohol metabolism. Among these metabolites, a significant positive correlation was found between allantoin, galactaric acid, gluconic acid, glucose, and drought tolerance. These metabolites may serve as markers of drought tolerance in genotype screening programs. Based on corresponding biological pathways analysis of the differentially abundant metabolites (DAMs), biosynthesis of alkaloid-derivatives of the shikimate pathway, fatty acid biosynthesis, purine metabolism, TCA cycle and amino acid biosynthesis were the most statistically enriched biological pathway in Azucena in drought response. However, in IR64, the differentially abundant metabolites of starch and sucrose metabolism were the most statistically enriched biological pathways.
conclusionMetabolic marker candidates for drought tolerance were identified in both genotypes. Thus, these markers that were experimentally determined in distinct metabolic pathways can be used for the development or selection of drought-tolerant rice genotypes.
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