ArticleNature medicine2023
Determinants of COVID-19 vaccine fatigue.
Article in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Effectiveness of stage-of-change (SOC)-tailored interventions in increasing uptake of any type of vaccination: A systematic review and meta-analysis.Applied psychology. Health and well-being · 2025Pooled it
- Preferences for COVID-19 Vaccines: Systematic Literature Review of Discrete Choice Experiments.JMIR public health and surveillance · 2024Pooled it
- A Hybrid Chatbot to Promote Pneumococcal Vaccination Among Older Adults: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Using positive imagination to reduce negativity in information processing and hesitant attitudes towards childhood COVID-19 vaccinations in parents: A randomized controlled trial.British journal of health psychology · 2025Trial
- Beyond seeking information: Lessons learned from a qualitative investigation of the information practices of parents about COVID-19 vaccination in Canada.Human vaccines & immunotherapeutics · 2026Article
- Dynamic trends and determinants of COVID-19 vaccine hesitancy among adults in China during 2021-2022: A multilevel analysis based on four national cross-sectional surveys.Human vaccines & immunotherapeutics · 2026Article
- Temporal Dynamics of Vaccine Uptake: Perceptual and Social Drivers of Adoption Speed Across Innovation Diffusion Curve.Microorganisms · 2026Article
- Emotions, preventive measures, and risk perception in post-emergency COVID-19: a cross-sectional study in Italian university staff during the seasonal vaccination campaign.BMC public health · 2026Article
- Advancing Vaccination Strategies for Older Adults: Insights of the Adult Immunization Board Meeting.Drugs & aging · 2026Review
- Hesitancy towards the COVID-19 booster vaccination: a thematic analysis from a focus group study in Spain.BMC public health · 2026Article
- Article
- Dose-dependent antiviral effects of glycyrrhizin, curcumin, and harmaline against clinical SARS-CoV-2 isolates, including D614G, Omicron BA.5, and Omicron XBB.1.BMC complementary medicine and therapies · 2026Article
- Effectiveness of mobile vaccination teams to increase COVID-19 booster uptake in Singapore: a population-based synthetic control study.BMC global and public health · 2026Article
- Pandemic fatigue and associated factors: a meta-analysis using the COM-B model.Frontiers in psychology · 2026Review
- Respiratory virus genomic epidemiology during post-pandemic re-emergence of influenza in Australia.Virus evolution · 2026Article
- From public healthcare centers to community pharmacies: the new Portuguese seasonal vaccination strategy.Frontiers in public health · 2026Article
- Recipient-focused interventions to increase vaccine uptake in high and upper-middle income countries: a systematic review and network meta-analysis.EClinicalMedicine · 2025Article
- Awareness and vaccination willingness of middle-aged and elderly individuals in Southwest China toward to herpes zoster vaccine.Human vaccines & immunotherapeutics · 2025Article
- Completion of Multidose COVID-19 Vaccination Among Adolescents and Adults in Urban Informal Settlements in Nairobi, Kenya.The American journal of tropical medicine and hygiene · 2025Article
- Challenges in coverage of future hepatitis C vaccines: Review and potential solutions.Vaccine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is growing concern that Coronavirus Disease 2019 (COVID-19) vaccine fatigue will be a major obstacle in maintaining immunity in the general population. In this study, we assessed vaccine acceptance in future scenarios in two conjoint experiments, investigating determinants such as new vaccines, communication, costs/incentives and legal rules. The experiments were embedded in an online survey (n = 6,357 participants) conducted in two European countries (Austria and Italy). Our results suggest that vaccination campaigns should be tailored to subgroups based on their vaccination status. Among the unvaccinated, campaign messages conveying community spirit had a positive effect (0.343, confidence interval (CI) 0.019-0.666), whereas offering positive incentives, such as a cash reward (0.722, CI 0.429-1.014) or voucher (0.670, CI 0.373-0.967), was pivotal to the decision-making of those vaccinated once or twice. Among the triple vaccinated, vaccination readiness increased when adapted vaccines were offered (0.279, CI 0.182-0.377), but costs (-0.795, CI -0.935 to -0.654) and medical dissensus (-0.161, CI -0.293 to -0.030) reduced their likelihood to get vaccinated. We conclude that failing to mobilize the triple vaccinated is likely to result in booster vaccination rates falling short of expectations. For long-term success, measures fostering institutional trust should be considered. These results provide guidance to those responsible for future COVID-19 vaccination campaigns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.