Evidence map›Paper›PMID 36973383›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Identification of clinical factors associated with timing and duration of spontaneous regression of retinopathy of prematurity not requiring treatment.

Jamee Schoephoerster, Sydney Roston, Scott Lunos, Sara E Ramel, Jill Anderson, Michael K Georgieff, Ellen C Ingolfsland

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jamee Schoephoerster *University of Minnesota Medical School, Minneapolis, MN, USA.
Sydney Roston *University of Minnesota Medical School, Minneapolis, MN, USA.ORCID 0000-0002-4421-3871
Scott LunosBiostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, USA.
Sara E RamelDepartment of Pediatrics, Division of Neonatology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-8485-418X
Jill AndersonDepartment of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
Michael K GeorgieffDepartment of Pediatrics, Division of Neonatology, University of Minnesota, Minneapolis, MN, USA.
Ellen C IngolfslandDepartment of Pediatrics, Division of Neonatology, University of Minnesota, Minneapolis, MN, USA. eingolf@umn.edu.ORCID 0000-0002-0940-9940

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
NCATS NIH HHS UL1 TR002494
6 · The paper itself

Abstract

objectiveIdentify clinical factors that delay or prolong spontaneous regression of retinopathy of prematurity (ROP). STUDY

designSecondary analysis of three prospective studies with 76 infants with ROP not requiring treatment, born ≤30 weeks postmenstrual age (PMA) and ≤1500 grams. Outcomes were PMA at greatest severity of ROP (PMA MSROP), at which regression began, at time of complete vascularization (PMA CV), and regression duration. Pearson's correlation coefficients, t-tests, or analyses of variance were calculated.

resultsIncreased positive bacterial cultures, hyperglycemia, transfusion volume of platelets and red blood cells and severity of ROP were associated with later PMA MSROP. Positive bacterial cultures, maternal chorioamnionitis, and less iron deficiency were associated with later PMA CV and prolonged regression duration. Slower length gain was associated with later PMA CV. P < 0.05 for all.

conclusionsPreterm infants with inflammatory exposures or linear growth impairment may require longer surveillance for ROP resolution and complete vascularization.

Indexed as

Retinopathy of PrematurityGestational AgeHumansInfantInfant, NewbornInfant, PrematureProspective StudiesRetrospective StudiesRisk Factors

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.