Evidence map›Paper›PMID 36973382›Full record

ArticleScientific reports2023

Application of machine learning in predicting non-alcoholic fatty liver disease using anthropometric and body composition indices.

Farkhondeh Razmpour, Reza Daryabeygi-Khotbehsara, Davood Soleimani, Hamzeh Asgharnezhad, Afshar Shamsi, Ghasem Sadeghi Bajestani, Mohsen Nematy, Mahdiyeh Razm Pour, Ralph Maddison, Sheikh Mohammed Shariful Islam

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In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Farkhondeh Razmpour *Department of Nutrition, Faculty of Medicine, Hormozgan University of Medical Sciences, Shahid Chamran Boulevard, Bandar Abbas, Iran. frazmpoor@gmail.com.
Reza Daryabeygi-Khotbehsara *Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong Victoria, Australia. reza.d@deakin.edu.au.
Davood SoleimaniDepartment of Nutrition, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Hamzeh AsgharnezhadInstitute for Intelligent Systems Research and Innovation (IISRI), Geelong Waurn Ponds Victoria, Australia.
Afshar ShamsiBiomedical Machine Learning Lab, University of New South Whales, Sydney, Australia.
Ghasem Sadeghi BajestaniDepartment of Biomedical Engineering, Faculty of Engineering, Imam Reza International University, Mashhad, Iran.
Mohsen NematyMetabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahdiyeh Razm PourDepartment of Electronic Learning, Shiraz University, Shiraz, Iran.
Ralph MaddisonInstitute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong Victoria, Australia.
Sheikh Mohammed Shariful IslamInstitute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong Victoria, Australia.
Deakin University · AUHormozgan University of Medical Sciences · IRImam Reza International University · IRKermanshah University of Medical Sciences · IRMashhad University of Medical Sciences · IRShiraz University · IRUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, which can progress from simple steatosis to advanced cirrhosis and hepatocellular carcinoma. Clinical diagnosis of NAFLD is crucial in the early stages of the disease. The main aim of this study was to apply machine learning (ML) methods to identify significant classifiers of NAFLD using body composition and anthropometric variables. A cross-sectional study was carried out among 513 individuals aged 13 years old or above in Iran. Anthropometric and body composition measurements were performed manually using body composition analyzer InBody 270. Hepatic steatosis and fibrosis were determined using a Fibroscan. ML methods including k-Nearest Neighbor (kNN), Support Vector Machine (SVM), Radial Basis Function (RBF) SVM, Gaussian Process (GP), Random Forest (RF), Neural Network (NN), Adaboost and Naïve Bayes were examined for model performance and to identify anthropometric and body composition predictors of fatty liver disease. RF generated the most accurate model for fatty liver (presence of any stage), steatosis stages and fibrosis stages with 82%, 52% and 57% accuracy, respectively. Abdomen circumference, waist circumference, chest circumference, trunk fat and body mass index were among the most important variables contributing to fatty liver disease. ML-based prediction of NAFLD using anthropometric and body composition data can assist clinicians in decision making. ML-based systems provide opportunities for NAFLD screening and early diagnosis, especially in population-level and remote areas.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdolescentBayes TheoremBody CompositionBody Mass IndexCross-Sectional StudiesHumansMachine Learning

Identifiers

PMID36973382
PMCPMC10043285
OpenAlexW4361005888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.