Evidence map›Paper›PMID 36973302›Full record

ArticleNPJ Parkinson's disease2023

Symptoms assessment and decision to treat patients with advanced Parkinson's disease based on wearables data.

Clara Virbel-Fleischman, Flavien Mousin, Shuo Liu, Sébastien Hardy, Jean-Christophe Corvol, Isabelle Benatru, David Bendetowicz, Matthieu Béreau, Valérie Cochen De Cock, Sophie Drapier and 5 more

Open access · goldFull text read
In one paragraph

Article in NPJ Parkinson's disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 3 countries.

Clara Virbel-FleischmanSorbonne University, Brain Institute - ICM, Inserm, CNRS, Paris, France. clara.virbel-fleischman@airliquide.com.ORCID http://orcid.org/0000-0002-3951-4653
Flavien MousinCentre EXPLOR!, Air Liquide Healthcare, Gentilly, France.
Shuo LiuCentre EXPLOR!, Air Liquide Healthcare, Gentilly, France.
Sébastien HardyCentre EXPLOR!, Air Liquide Healthcare, Gentilly, France.
Jean-Christophe CorvolSorbonne University, Brain Institute - ICM, Inserm, CNRS, Paris, France.
Isabelle BenatruPoitiers University Hospital, Neurology Department, Poitiers, France.
David BendetowiczSorbonne University, Brain Institute - ICM, Inserm, CNRS, Paris, France.ORCID http://orcid.org/0000-0002-6310-1250
Matthieu BéreauBesançon CHRU, Neurology Department, Besançon, France.
Valérie Cochen De CockBeau Soleil Clinic, Sleep et Neurology Department, Montpellier, France.
Sophie DrapierRennes CHU, Neurology Department, Rennes, France.
Solène FrismandNancy CHRU, Neurology Department, Nancy, France.
Caroline GiordanaNice University Hospital, Neurology Department, Nice, France.
David DevosLille University, Lille CHU, Inserm, U1172, Lille Neuroscience & Cognition, NS-park F-CRIN network, LICEND, Lille, France.ORCID http://orcid.org/0000-0002-2417-799X
Yann RétoryCentre EXPLOR!, Air Liquide Healthcare, Gentilly, France.
David GrabliSorbonne University, Brain Institute - ICM, Inserm, CNRS, Paris, France.
Centre National de la Recherche Scientifique · FRAir Liquide (France) · FRInserm · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Nice · FRCentre Hospitalier Universitaire de Rennes · FRUniversité de Montpellier · FRUniversité d'Orléans · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Body-worn sensors (BWS) could provide valuable information in the management of Parkinson's disease and support therapeutic decisions based on objective monitoring. To study this pivotal step and better understand how relevant information is extracted from BWS results and translated into treatment adaptation, eight neurologists examined eight virtual cases composed of basic patient profiles and their BWS monitoring results. Sixty-four interpretations of monitoring results and the subsequent therapeutic decisions were collected. Relationship between interrater agreements in the BWS reading and the severity of symptoms were analyzed via correlation studies. Logistic regression was used to identify associations between the BWS parameters and suggested treatment modifications. Interrater agreements were high and significantly associated with the BWS scores. Summarized BWS scores reflecting bradykinesia, dyskinesia, and tremor predicted the direction of treatment modifications. Our results suggest that monitoring information is robustly linked to treatment adaptation and pave the way to loop systems able to automatically propose treatment modifications from BWS recordings information.

Identifiers

PMID36973302
PMCPMC10042860
OpenAlexW4361003845

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read18
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.