ArticleNature communications2023
Risk of death following COVID-19 vaccination or positive SARS-CoV-2 test in young people in England.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Cardiology Consult for the General Pediatrician after Cardiac Manifestations from a SARS-CoV-2 Infection.Current pediatric reviews · 2026Pooled it
- Vitamin D Deficiency Meets Hill's Criteria for Causation in SARS-CoV-2 Susceptibility, Complications, and Mortality: A Systematic Review.Nutrients · 2025Pooled it
- Risk of all-cause and cardiac-related mortality after vaccination against COVID-19: A meta-analysis of self-controlled case series studies.Human vaccines & immunotherapeutics · 2023Pooled it
- An updated meta-analysis of Chinese herbal medicine for the prevention of COVID-19 based on Western-Eastern medicine.Frontiers in pharmacology · 2023Pooled it
- Response to the letter to the editor by J. Aarstad.European journal of epidemiology · 2026Article
- Can we rule out that COVID-19-vaccination did not increase all-cause mortality?European journal of epidemiology · 2026Article
- Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study.PLoS medicine · 2026Article
- COVID-19 vaccination and short-term mortality risk: a nationwide self-controlled case series study in The Netherlands.European journal of epidemiology · 2026Article
- COVID-19 mRNA Vaccination and 4-Year All-Cause Mortality Among Adults Aged 18 to 59 Years in France.JAMA network open · 2025Article
- Clustering-based methodology for comparing multi-characteristic epidemiological dynamics with application to COVID-19 epidemiology in Europe.Royal Society open science · 2025Article
- Tinnitus risk after COVID-19 XBB.1.5 vaccination: A self-controlled case series study.Vaccine · 2025Article
- Socioeconomic and temporal heterogeneity in SARS-CoV-2 exposure and disease in England from May 2020 to February 2023.Science advances · 2025Article
- Association between mRNA COVID-19 vaccine boosters and mortality in Japan: The VENUS study.Human vaccines & immunotherapeutics · 2024Article
- Unveiling the Interplay-Vitamin D and ACE-2 Molecular Interactions in Mitigating Complications and Deaths from SARS-CoV-2.Biology · 2024Review
- Article
- Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England.Nature communications · 2024Article
- Pfizer COVID19 vaccine is not associated with acute cardiovascular events excluding myocarditis- a national self-controlled case series study.Israel journal of health policy research · 2024Article
- Article
- Article
- Deaths among young people in England increased significantly in 10 of 11 weeks after COVID-19 vaccination and doubled in three.EXCLI journal · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have reported associations between COVID-19 vaccination and risk of cardiac diseases, especially in young people; the impact on mortality, however, remains unclear. We use national, linked electronic health data in England to assess the impact of COVID-19 vaccination and positive SARS-CoV-2 tests on the risk of cardiac and all-cause mortality in young people (12 to 29 years) using a self-controlled case series design. Here, we show there is no significant increase in cardiac or all-cause mortality in the 12 weeks following COVID-19 vaccination compared to more than 12 weeks after any dose. However, we find an increase in cardiac death in women after a first dose of non mRNA vaccines. A positive SARS-CoV-2 test is associated with increased cardiac and all-cause mortality among people vaccinated or unvaccinated at time of testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.