Evidence map›Paper›PMID 36973246›Full record

ArticleNature communications2023

The genomic epidemiology of Escherichia albertii infecting humans and birds in Great Britain.

Rebecca J Bengtsson, Kate S Baker, Andrew A Cunningham, David R Greig, Shinto K John, Shaheed K Macgregor, Katharina Seilern-Moy, Simon Spiro, Charlotte C Chong, P Malaka De Silva and 2 more

Open access · goldFull text read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Integrated study on the occurrence and genomic features ofApplied and environmental microbiology · 2026
    Article
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  3. First report ofASM case reports · 2025
    Article
  4. Article
  5. Whole-genome-based characterization ofMicrobial genomics · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Rebecca J BengtssonClinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, The University of Liverpool, Liverpool, UK.
Kate S BakerClinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, The University of Liverpool, Liverpool, UK. kbaker@liverpool.ac.uk.ORCID 0000-0001-5850-1949
Andrew A CunninghamInstitute of Zoology, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.ORCID 0000-0002-3543-6504
David R GreigGastrointestinal and Food Safety (One Health) Division, UK Health Security Agency, Colindale, London, UK.
Shinto K JohnInstitute of Zoology, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.
Shaheed K MacgregorWildlife Health Services, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.
Katharina Seilern-MoyInstitute of Zoology, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.
Simon SpiroWildlife Health Services, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.
Charlotte C ChongClinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, The University of Liverpool, Liverpool, UK.
P Malaka De SilvaClinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, The University of Liverpool, Liverpool, UK.
Claire JenkinsGastrointestinal and Food Safety (One Health) Division, UK Health Security Agency, Colindale, London, UK.
Becki LawsonInstitute of Zoology, Zoological Society of London, Regent's Park, London, NW1 4RY, UK.
Zoological Society of London · GBUniversity of Liverpool · GBUK Health Security Agency · GB

Funding

Biotechnology and Biological Sciences Research Council BB/V009184/1Medical Research Council MR/R020787/1
6 · The paper itself

Abstract

Escherichia albertii is a recently identified gastrointestinal bacterial pathogen of humans and animals which is typically misidentified as pathotypes of diarrhoeagenic Escherichia coli or Shigella species and is generally only detected during genomic surveillance of other Enterobacteriaceae. The incidence of E. albertii is likely underestimated, and its epidemiology and clinical relevance are poorly characterised. Here, we whole genome sequenced E. albertii isolates from humans (n = 83) and birds (n = 79) isolated in Great Britain between 2000 and 2021 and analysed these alongside a broader public dataset (n = 475) to address these gaps. We found human and avian isolates typically (90%; 148/164) belonged to host-associated monophyletic groups with distinct virulence and antimicrobial resistance profiles. Overlaid patient epidemiological data suggested that human infection was likely related to travel and possibly foodborne transmission. The Shiga toxin encoding stx2f gene was associated with clinical disease (OR = 10.27, 95% CI = 2.98-35.45 p = 0.0002) in finches. Our results suggest that improved future surveillance will further elucidate disease ecology and public and animal health risks associated with E. albertii.

Indexed as

Enterobacteriaceae InfectionsEscherichia coli InfectionsAnimalsBirdsEscherichiaEscherichia coliGenomicsHumansUnited Kingdom

Identifiers

PMID36973246
PMCPMC10043262
OpenAlexW4360989994

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read55
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.