Evidence map›Paper›PMID 36973065›Full record

SynthesisAnnals of family medicine

Vaginal Swab vs Urine for Detection of

Kristal J Aaron, Stacey Griner, Alison Footman, Alexander Boutwell, Barbara Van Der Pol

Open access · diamondAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Point-of-care Tests for Chlamydia trachomatis and Neisseria gonorrhoeae: Review of the Literature.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Pooled it
  3. Pooled it
  4. Analysis of minimum inhibitory concentrations of azithromycin, ceftriaxone and ciprofloxacin forEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Review
  13. UnveilingiScience · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Clinical Updates in Sexually Transmitted Infections, 2024.Journal of women's health (2002) · 2024
    Review
  19. Review
  20. Detection ofPathogens (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kristal J AaronUniversity of Alabama at Birmingham, Department of Medicine, Division of Infectious Diseases, Heersink School of Medicine, Birmingham, Alabama kjaaron@uabmc.edu.
Stacey GrinerUniversity of North Texas Health Science Center School of Public Health, Fort Worth, Texas.
Alison FootmanUniversity of Alabama at Birmingham School of Public Health, Birmingham, Alabama.
Alexander BoutwellUniversity of Alabama at Birmingham, Department of Medicine, Division of Infectious Diseases, Heersink School of Medicine, Birmingham, Alabama.
Barbara Van Der PolUniversity of Alabama at Birmingham, Department of Medicine, Division of Infectious Diseases, Heersink School of Medicine, Birmingham, Alabama.
University of Alabama at Birmingham · USUniversity of North Texas Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsA systematic search of multiple databases from 1995 through 2021 identified studies that (1) evaluated commercially available assays, (2) presented data for women, (3) included data obtained from the same assay on both a urine specimen and a vaginal swab from the same patient, (4) used a reference standard, and (5) were published in English. We calculated pooled estimates for sensitivity and the corresponding 95% CIs for each pathogen as well as odds ratios for any difference in performance.

resultsWe identified 28 eligible articles with 30 comparisons for CT, 16 comparisons for NG, and 9 comparisons for TV. Pooled sensitivity estimates for vaginal swabs and urine, respectively, were 94.1% and 86.9% for CT, 96.5% and 90.7% for NG, and 98.0% and 95.1% for TV (all

conclusionsEvidence from this analysis supports the Centers for Disease Control and Prevention's recommendation that vaginal swabs are the optimal sample type for women being tested for chlamydia, gonorrhea, and/or trichomoniasis.

Indexed as

Chlamydia InfectionsGonorrheaSexually Transmitted DiseasesTrichomonas vaginalisChlamydia trachomatisFemaleHumansNeisseria gonorrhoeaeChlamydia trachomatisNeisseria gonorrhoeaeTrichomonas vaginaliswomen’s health

Identifiers

PMID36973065
PMCPMC10042575
OpenAlexW4360991868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.