Evidence map›Paper›PMID 36973004›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Race and Ethnicity in Pulmonary Function Test Interpretation: An Official American Thoracic Society Statement.

Nirav R Bhakta, Christian Bime, David A Kaminsky, Meredith C McCormack, Neeta Thakur, Sanja Stanojevic, Aaron D Baugh, Lundy Braun, Stephanie Lovinsky-Desir, Rosemary Adamson and 21 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed, 3 pooled it
64.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 3 syntheses or guidelines pooled it, 251 citations in OpenAlex.

  1. Pooled it
  2. New spirometry recommendations from the Brazilian Thoracic Association - 2024 update.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Guideline
  3. Race-Based Pulmonary Function Testing Correction in COPD Inhaler Therapy Trials: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2024
    Pooled it
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  19. Associations between genetic ancestry and allergic outcomes at 10 years among Black children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  20. Article

101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 1 institution in 1 country.

Christian Bime
David A Kaminsky
Meredith C McCormack
Sanja Stanojevic
Aaron D Baugh
Lundy Braun
Stephanie Lovinsky-DesirORCID 0000-0003-2272-4387
Rosemary Adamson
Jonathan Witonsky
Robert A Wise
Sean D Levy
Robert Brown
Erick Forno
Robyn T Cohen
Meshell Johnson
John Balmes
Yolanda Mageto
Cathryn T Lee
Refiloe Masekela
Daniel J Weiner
Charlie G Irvin
Erik R Swenson
Margaret Rosenfeld
Richard M Schwartzstein
Anurag Agrawal
Enid Neptune
Juan P Wisnivesky
Victor E Ortega
Peter Burney
University of California, San Francisco · US

Funding

S-glutathionylation chemistry, glycolysis and obese allergic asthmaR01HL137268 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI DIXON, ANNE E, VAN DER VLIET, ALBERT · 2017 to 2020
$2.1M
SELPLG as a candidate gene in Acute Respiratory Distress SyndromeK08HL141623 · NHLBI · UNIVERSITY OF ARIZONA · PI BIME, CHRISTIAN · 2018 to 2022
$863k
NHLBI NIH HHS K08 HL141623NHLBI NIH HHS R01 HL137268
6 · The paper itself

Abstract

Current American Thoracic Society (ATS) standards promote the use of race and ethnicity-specific reference equations for pulmonary function test (PFT) interpretation. There is rising concern that the use of race and ethnicity in PFT interpretation contributes to a false view of fixed differences between races and may mask the effects of differential exposures. This use of race and ethnicity may contribute to health disparities by norming differences in pulmonary function. In the United States and globally, race serves as a social construct that is based on appearance and reflects social values, structures, and practices. Classification of people into racial and ethnic groups differs geographically and temporally. These considerations challenge the notion that racial and ethnic categories have biological meaning and question the use of race in PFT interpretation. The ATS convened a diverse group of clinicians and investigators for a workshop in 2021 to evaluate the use of race and ethnicity in PFT interpretation. Review of evidence published since then that challenges current practice and continued discussion concluded with a recommendation to replace race and ethnicity-specific equations with race-neutral average reference equations, which must be accompanied with a broader re-evaluation of how PFTs are used to make clinical, employment, and insurance decisions. There was also a call to engage key stakeholders not represented in this workshop and a statement of caution regarding the uncertain effects and potential harms of this change. Other recommendations include continued research and education to understand the impact of the change, to improve the evidence for the use of PFTs in general, and to identify modifiable risk factors for reduced pulmonary function.

Indexed as

EthnicitySocietiesHumansRespiratory Function TestsUnited StatesethnicityinterpretationPFTrace

Identifiers

PMID36973004
PMCPMC10112445
OpenAlexW4360989948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.