Evidence map›Paper›PMID 36972975›Full record

ArticleOccupational and environmental medicine2023

All-cause and cause-specific mortality in a cohort of WTC-exposed and non-WTC-exposed firefighters.

Ankura Singh, Rachel Zeig-Owens, Madeline Cannon, Mayris P Webber, David G Goldfarb, Robert D Daniels, David J Prezant, Paolo Boffetta, Charles B Hall

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ankura SinghBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.
Rachel Zeig-OwensBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA rachel.zeig-owens@fdny.nyc.gov.ORCID 0000-0002-8679-2306
Madeline CannonBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.
Mayris P WebberBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.
David G GoldfarbBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.ORCID 0000-0003-2682-7543
Robert D DanielsDivision of Science integration, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.ORCID 0000-0002-3915-7991
David J PrezantBureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, Stony Brook, New York, USA.
Charles B HallDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0001-9982-8120

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Mortality among WTC rescue and recovery workersU01OH011480 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOFFETTA, PAOLO, HALL, CHARLES B · 2017 to 2020
$2.4M
Maintenance and Extension of a Cohort of Career Firefighters as a Non-WTC Exposed Comparison for the FDNY Firefighter CohortU01OH011309 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WEBBER, MAYRIS P · 2016 to 2018
$1.6M
Maintenance and Extension of a Cohort of Career Firefighters as a Non-WTC Exposed Comparison for the FDNY Firefighter CohortU01OH011934 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI WEBBER, MAYRIS P · 2019 to 2021
$1.4M
COOPERATIVE RESEARCH AGREEMENTS RELATED TO THE WORLD TRADE CENTER HEALTH PROGRAM (U01)U01OH012235 · OH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BOFFETTA, PAOLO · 2021 to 2021
$931k
ACL HHS U01OH011309ACL HHS U01OH011480NCI NIH HHS P30 CA008748NIOSH CDC HHS U01 OH011309NIOSH CDC HHS U01 OH011480NIOSH CDC HHS U01 OH011934NIOSH CDC HHS U01 OH012235
6 · The paper itself

Abstract

objectiveTo compare mortality rates in World Trade Center (WTC)-exposed Fire Department of the City of New York (FDNY) firefighters with rates in similarly healthy, non-WTC-exposed/non-FDNY firefighters, and compare mortality in each firefighter cohort with the general population.

methods10 786 male WTC-exposed FDNY firefighters and 8813 male non-WTC-exposed firefighters from other urban fire departments who were employed on 11 September 2001 were included in the analyses. Only WTC-exposed firefighters received health monitoring via the WTC Health Programme (WTCHP). Follow-up began 11 September 2001 and ended at the earlier of death date or 31 December 2016. Death data were obtained from the National Death Index and demographics from the fire departments. We estimated standardised mortality ratios (SMRs) in each firefighter cohort versus US males using demographic-specific US mortality rates. Poisson regression models estimated relative rates (RRs) of all-cause and cause-specific mortality in WTC-exposed versus non-WTC-exposed firefighters, controlling for age and race.

resultsBetween 11 September 2001 and 31 December 2016, there were 261 deaths among WTC-exposed firefighters and 605 among non-WTC-exposed. Both cohorts had reduced all-cause mortality compared with US males (SMR (95% CI)=0.30 (0.26 to 0.34) and 0.60 (0.55 to 0.65) in WTC-exposed and non-WTC-exposed, respectively). WTC-exposed firefighters also had lower rates of all-cause mortality (RR=0.54, 95% CI=0.49 to 0.59) and cancer-specific, cardiovascular-specific and respiratory disease-specific mortality compared with non-WTC-exposed firefighters.

conclusionBoth firefighter cohorts had lower than expected all-cause mortality. Fifteen years post 11 September 2001, mortality was lower in WTC-exposed versus non-WTC-exposed firefighters. Lower mortality in the WTC-exposed suggests not just a healthy worker effect, but additional factors such as greater access to free health monitoring and treatment that they receive via the WTCHP.

Indexed as

FirefightersNeoplasmsOccupational ExposureSeptember 11 Terrorist AttacksCause of DeathHumansMaleNew YorkNew York CityRescue Workepidemiologyfirefightersmortalityoccupational health

Identifiers

PMID36972975
PMCPMC10523283

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.