Evidence map›Paper›PMID 36972969›Full record

ArticleBMJ open2023

How does discharge against medical advice affect risk of mortality and unplanned readmission? A retrospective cohort study set in a large UK medical admissions unit.

Anand Alagappan, Thomas J G Chambers, Erik Brown, Sheila M Grecian, Khalida Ann Lockman

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  7. The Unhoused Burn Population: An Alarming Increase of Leaving Against Medical Advice.Journal of burn care & research : official publication of the American Burn Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anand AlagappanAcute & General Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.ORCID 0000-0002-0676-0006
Thomas J G ChambersCentre for Discovery Brain Sciences, The University of Edinburgh, Edinburgh, UK tom.chambers@ed.ac.uk.
Erik BrownLothian Analytical Services, Waverley Gate, NHS Lothian, Edinburgh, UK.
Sheila M GrecianMetabolic Unit, Western General Hospital, Edinburgh, UK.
Khalida Ann LockmanAcute & General Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Edinburgh Royal Infirmary · GBWestern General Hospital · GBNHS Lothian · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesTo assess the frequency of discharge against medical advice (DAMA) in a large UK teaching hospital, explore factors which increase the risk of DAMA and identify how DAMA impacts patient risk of mortality and readmission.

designRetrospective cohort study.

settingLarge acute teaching hospital in the UK. PATIENTS: 36 683 patients discharged from the acute medical unit of a large UK teaching hospital between 1 January 2012 and 31 December 2016. MEASUREMENTS: Patients were censored on 1 January 2021. Mortality and 30-day unplanned readmission rates were assessed. Deprivation, age and sex were taken as covariates.

results3% of patients discharged against medical advice. These patients were younger (median age (years) (IQR)): planned discharge (PD) 59 (40-77); DAMA 39 (28-51), predominantly of male sex (PD 48%; DAMA 66%) and were of greater social deprivation (in three most deprived quintiles PD 69%; DAMA 84%). DAMA was associated with increased risk of death in patients under the age of 33.3 years (adjusted HR 2.6 (1.2-5.8)) and increased incidence of 30-day readmission (standardised incidence ratio 1.9 (1.5-2.2)). LIMITATIONS: Readmission to acute hospitals outside of the local health board may have been missed. We were unable to include information regarding comorbidity or severity of presentation.

conclusionsThese data highlight the vulnerability of younger patients who DAMA, even in a free-at-the-point-of-delivery healthcare setting.

Indexed as

Patient DischargePatient ReadmissionAdultHospitals, TeachingHumansMaleRetrospective StudiesUnited KingdomHealth economicsINTERNAL MEDICINEPUBLIC HEALTH

Identifiers

PMID36972969
PMCPMC10069606
OpenAlexW4360999754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.