ArticleBMJ open2023
Association between periodontitis and hypertension: cross-sectional survey from the Fourth National Oral Health Survey of China (2015-2016).
Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 9 citations in OpenAlex.
- Palm Mixed-Carotenes Modulate Viability, Wound Closure and Osteoprotegerin mRNA Expression in Human Periodontal Ligament Stem Cells.Biomedicines · 2026Article
- [Preparation of B@PH/GM-V hydrogel microspheres and their antioxidant and osteogenesis-promoting effects].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Article
- Association Between Arterial Hypertension and Periodontitis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Article
- Associations between periodontitis and postoperative infectious complications in OSCC patients: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Hypertension as a risk factor for periodontitis.Bioinformation · 2026Article
- Cost-Effectiveness of promoting preventive oral self-care in China: a population-based modelling study.BMJ public health · 2026Article
- Graphene quantum dots remodel osteogenesis of human periodontal ligament stem cells under inflammatory microenvironment: anFrontiers in bioengineering and biotechnology · 2026Article
- Assessing the impact of systemic conditions on periodontal health in Malaysian population: a retrospective study.BMC oral health · 2024Article
- Mouth-Heart Connection: A Systematic Review on the Impact of Periodontal Disease on Cardiovascular Health.Cureus · 2023Review
- Mapping Oral Frailty Research in the Elderly (1997-2024): A Comparative Bibliometric Analysis of China and the International Landscape.Public health nursing (Boston, Mass.)Review
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Authors and funding
16 authors at 8 institutions in 4 countries.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the association between periodontitis severity and hypertension based on Chinese epidemiological data.
designThis cross-sectional survey enrolled adults from the Fourth National Oral Health Survey of China (2015-2016).
settingThe data were obtained from the Fourth National Oral Health Survey of China (2015-2016).
participantsThe study included individuals aged 35-44 years (n=4409), 55-64 years (n=4568) and 65-74 years (n=4218). PRIMARY AND SECONDARY OUTCOME MEASURES: Periodontal status, defined on the basis of the 2017 classification scheme, and periodontal parameters (eg, bleeding on probing (BOP)) were compared between individuals with hypertension and individuals with normotension. Smoothed scatterplots were constructed to demonstrate the associations of periodontal parameters and periodontal status with hypertension.
resultsSevere periodontitis (stages III and IV) was present in 41.4% of individuals with hypertension and 28.0% of individuals with normotension, respectively (p<0.001). The prevalence of severe periodontitis was higher in individuals with hypertension than that in individuals with normotension among participants aged 35-44 years (18.0% vs 10.1%, p<0.001) and 55-64 years (40.2% vs 36.7%, p=0.035), but not in participants aged 65-74 years (46.4% vs 45.1%, p=0.429). Therefore, the difference in periodontal status between individuals with hypertension and individuals with normotension decreased with age. There were higher prevalences of BOP, probing depth (PD) ≥4 mm and PD ≥6 mm in individuals with hypertension than in individuals with normotension (52.1% vs 49.2%, 19.6% vs 14.7% and 1.8% vs 1.1%, respectively). Periodontitis severity and the proportion of teeth with PD ≥4 or ≥6 mm were positively associated with hypertension.
conclusionPeriodontitis is associated with hypertension in Chinese adults. Hypertension prevalence increased with periodontitis severity, particularly among young participants. Accordingly, it is necessary to improve the education, awareness of periodontal treatment and preventive management among individuals at risk of hypertension, particularly in the younger population.
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