Evidence map›Paper›PMID 36972966›Full record

ArticleBMJ open2023

Service delivery models that promote linkages to PrEP for adolescent girls and young women and men in sub-Saharan Africa: a scoping review.

Trisha Ramraj, Witness Chirinda, Kim Jonas, Darshini Govindasamy, Ngcwalisa Jama, Tracy McClinton Appollis, Babalwa Zani, Ferdinand C Mukumbang, Wisdom Basera, Mbuzeleni Hlongwa and 3 more

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Trisha Ramraj *HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Durban, KwaZulu-Natal, South Africa trisha.ramraj@mrc.ac.za.ORCID 0000-0003-2165-9376
Witness Chirinda *Health Systems Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Kim JonasHealth Systems Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.ORCID 0000-0002-4469-6674
Darshini GovindasamyHealth Systems Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Ngcwalisa JamaBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Tracy McClinton AppollisHealth Systems Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Babalwa ZaniBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Ferdinand C MukumbangBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.ORCID 0000-0003-1441-2172
Wisdom BaseraBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Mbuzeleni HlongwaBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Eunice B TurawaBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Catherine MathewsHealth Systems Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.
Edward NicolBurden of Disease Research Unit, South African Medical Research Council, Tygerberg, Western Cape, South Africa.ORCID 0000-0001-6019-9259

Funding

CDC HHS NU2GGH002093
6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) is an emerging biomedical prevention intervention. Documenting PrEP service delivery models (SDMs) that promote linkage to and continuation of PrEP will inform guidelines and maximise roll-out.

objectivesTo synthesise and appraise the effectiveness and feasibility of PrEP SDMs designed to promote linkage to PrEP care among adolescent girls and young women (AGYW) and men in sub-Saharan Africa (SSA). ELIGIBILITY CRITERIA: Primary quantitative and qualitative studies published in English and conducted in SSA were included. No restrictions on the date of publication were applied. SOURCES OF EVIDENCE: Methodology outlined in the Joanna Briggs Institute reviewers' manual was followed. PubMed, Cochrane library, Scopus, Web of Science and online-conference abstract archives were searched. CHARTING

methodsData on article, population, intervention characteristics and key outcomes was charted in REDCap. RESULTS AND

conclusionOf the 1204 identified records, 37 (met the inclusion criteria. Health facility-based integrated models of PrEP delivery with family planning, maternal and child health or sexual and reproductive services to AGYW resulted in PrEP initiation of 16%-90%. Community-based drop-in centres (66%) was the preferred PrEP outlet for AGYW compared with public clinics (25%) and private clinics (9%). Most men preferred community-based delivery models. Among individuals who initiated PrEP, 50% were men, 62% were <35 years old and 97% were tested at health fairs compared with home testing. Integrated antiretroviral therapy (ART)-PrEP delivery was favoured among serodiscordant couples with 82.9% of couples using PrEP or ART with no HIV seroconversions. PrEP initiation within healthcare facilities was increased by perceived client-friendly services and non-judgemental healthcare workers. Barriers to PrEP initiation included distance to travel to and time spent at health facilities and perceived community stigma. PrEP SDMs for AGYW and men need to be tailored to the needs and preferences for each group. Programme implementers should promote community-based SDMs to increase PrEP initiation among AGYW and men.

Indexed as

Anti-HIV AgentsHIV InfectionsHIV SeropositivityPre-Exposure ProphylaxisAdolescentAdultAfrica South of the SaharaChildFemaleHumansMaleSexual BehaviorAnti-HIV AgentsHIV & AIDSpublic health

Identifiers

PMID36972966
PMCPMC10069497

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.