Evidence map›Paper›PMID 36972760›Full record

GuidelineChest2023

Effect of Race and Ethnicity on Pulmonary Function Testing Interpretation: An American College of Chest Physicians (CHEST), American Association for Respiratory Care (AARC), American Thoracic Society (ATS), and Canadian Thoracic Society (CTS) Evidence Review and Research Statement.

Darcy D Marciniuk, Ellen A Becker, David A Kaminsky, Meredith C McCormack, Sanja Stanojevic, Nirav R Bhakta, Christian Bime, Vikram Comondore, Clayton T Cowl, Sharon Dell and 6 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Chest, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Implications of removing race from spirometry reference equations in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 2 countries.

Darcy D MarciniukDivision of Respirology, Critical Care and Sleep Medicine, Respiratory Research Center, University of Saskatchewan, Saskatoon, SK. Electronic address: Darcy.marciniuk@usask.ca.
Ellen A BeckerDivision of Respiratory Care, Department of Cardiopulmonary Sciences Rush University, Chicago, IL.
David A KaminskyPulmonary and Critical Care, University of Vermont Larner College of Medicine, Burlington, VT.
Meredith C McCormackPulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Sanja StanojevicDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, NS.
Nirav R BhaktaDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA.
Christian BimeUniversity of Arizona College of Medicine, Tucson, AZ.
Vikram ComondoreDivision of Respirology, McMaster University, Hamilton, ON; Division of Respirology, William Osler Health System, Brampton, ON.
Clayton T CowlDivision of Public Health, Infectious Diseases and Occupational Medicine and the Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Sharon DellDepartment of Pediatrics and BC Children's Research Institute, University of British Columbia, Vancouver, BC, Canada.
Jeffrey HaynesPulmonary Function Laboratory, Elliot Health System, Manchester, NH.
Fred JaffeTemple University Hospital, Philadelphia, PA.
Carl MottramPFW Consulting LLC, Hayfield, MN.
Nneka SederstromHealth Equity Department, Hennepin Healthcare, Minneapolis, MN.
Mary TownsendM.C. Townsend Associates, LLC, Pittsburgh, PA; University of Pittsburgh School of Public Health, Pittsburgh, PA.
Jonathan M IaccarinoAmerican College of Chest Physicians, Chicago, IL; Chobanian and Avedisian School of Medicine, Boston University, Boston, MA.
Boston University · USDalhousie University · CAElliot Hospital · USHennepin Healthcare Research Institute · USJohns Hopkins University · USMayo Clinic in Florida · USRush University · USTemple University Hospital · USUniversity of Arizona · USUniversity of British Columbia · CAUniversity of California, San Francisco · USUniversity of Pittsburgh · USUniversity of Saskatchewan · CAUniversity of Vermont · USWilliam Osler Health System · CA

Funding

SELPLG as a candidate gene in Acute Respiratory Distress SyndromeK08HL141623 · NHLBI · UNIVERSITY OF ARIZONA · PI BIME, CHRISTIAN · 2018 to 2022
$863k
NHLBI NIH HHS K08 HL141623
6 · The paper itself

Abstract

backgroundCalls have been made to discontinue the routine use of race and ethnicity in medicine. Specific to respiratory medicine, the use of race- and ethnicity-specific reference equations for the interpretation of pulmonary function test (PFT) results has been questioned. RESEARCH QUESTIONS: Three key questions were addressed: (1) What is the current evidence supporting the use of race- and ethnicity-specific reference equations for the interpretation of PFTs? (2) What are the potential clinical implications of the use or nonuse of race and ethnicity in interpreting PFT results? and (3) What research gaps and questions must be addressed and answered to understand better the effect of race and ethnicity on PFT results interpretation and potential clinical and occupational health implications? STUDY DESIGN AND

methodsA joint multisociety (American College of Chest Physicians, American Association for Respiratory Care, American Thoracic Society, and Canadian Thoracic Society) expert panel was formed to undertake a comprehensive evidence review and to develop a statement with recommendations to address the research questions.

resultsSeveral assumptions and gaps, both in the published literature and in our evolving understanding of lung health, were identified. It seems that many past perceptions and practices regarding the effect of race and ethnicity on PFT results interpretation are based on limited scientific evidence and measures that lack reliability.

interpretationA need exists for more and better research that will inform our field about these many uncertainties and will serve as a foundation for future recommendations in this area. The identified shortcomings should not be discounted or dismissed because they may enable flawed conclusions, unintended consequences, or both. Addressing the identified research gaps and needs would allow a better-a more informed-understanding of the effects of race and ethnicity on PFT results interpretation.

Indexed as

EthnicityPhysiciansCanadaHumansReproducibility of ResultsRespiratory Function TestsUnited Statesethnicityinterpretationpulmonary function testingraceresearch

Identifiers

PMID36972760
PMCPMC10475820
OpenAlexW4360955442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.