Evidence map›Paper›PMID 36972460›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Intrinsically disordered proteins SAID1/2 condensate on SERRATE for dual inhibition of miRNA biogenesis in Arabidopsis.

Baoshuan Shang, Lin Wang, Xingxing Yan, Yanjun Li, Changhao Li, Chaohua Wu, Tian Wang, Xiang Guo, Suk Won Choi, Tianru Zhang and 7 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  8. Review
  9. Intrinsically disordered proteins SAID1/2 condensate on SERRATE for dual inhibition of miRNA biogenesis in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Baoshuan ShangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-8744-3554
Lin WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.ORCID 0000-0001-7787-904X
Xingxing YanDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-0140-4029
Yanjun LiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Changhao LiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Chaohua WuDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Tian WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Xiang GuoKey Laboratory of Plant Stress Biology, State Key Laboratory of Cotton Biology, School of Life Sciences, Henan University, Kaifeng 475004, China.
Suk Won ChoiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Tianru ZhangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Ziying WangDepartment of Biology, Texas A&M University, College Station, TX 77843.
Chun-Yip TongDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Taerin OhDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Xiao ZhangKey Laboratory of Plant Stress Biology, State Key Laboratory of Cotton Biology, School of Life Sciences, Henan University, Kaifeng 475004, China.
Zhiye WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Xu PengDepartment of Medical Physiology, School of Medicine, Texas A&M University, Bryan, TX 77807.ORCID 0000-0001-9068-102X
Xiuren ZhangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.
Texas A&M University · USHenan University · CNState Key Laboratory of Plant Physiology and BiochemistryBryan College · USNingbo University · CNShandong Normal University · CN

Funding

Roles of SWI/SNF complexes in posttranscriptional processing of RNAR01GM132401 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2019 to 2022
$1.4M
Suppression mechanism of Geminivirus-encoded TrAP proteinR01GM127742 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2019 to 2022
$1.2M
NIGMS NIH HHS R01 GM127742NIGMS NIH HHS R01 GM132401
6 · The paper itself

Abstract

Intrinsically disordered proteins (IDPs) SAID1/2 are hypothetic dentin sialophosphoprotein-like proteins, but their true functions are unknown. Here, we identified SAID1/2 as negative regulators of SERRATE (SE), a core factor in miRNA biogenesis complex (microprocessor). Loss-of-function double mutants of

Indexed as

ArabidopsisArabidopsis ProteinsIntrinsically Disordered ProteinsMicroRNAsGene Expression Regulation, PlantRibonuclease IIIRNA-Binding ProteinsRNA Processing, Post-TranscriptionalArabidopsis ProteinsIntrinsically Disordered ProteinsMicroRNAsRibonuclease IIIRNA-Binding ProteinsArabidopsisintrinsically disordered proteinphase separationphosphorylationRNA silencing

Identifiers

PMID36972460
PMCPMC10083546
OpenAlexW4360992865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.