Evidence map›Paper›PMID 36972322›Full record

ReviewMicrobiology (Reading, England)2023

Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies?

Mohd Athar, Silvia Gervasoni, Andrea Catte, Andrea Basciu, Giuliano Malloci, Paolo Ruggerone, Attilio Vittorio Vargiu

Open access · diamondAbstract readReview
In one paragraph

Review in Microbiology (Reading, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Resistance ofAntibiotics (Basel, Switzerland) · 2025
    Article
  8. Recent advances in anti-infective drug discovery · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Di-berberine conjugates as chemical probes ofbioRxiv : the preprint server for biology · 2023
    Article
  13. Microbial Musings: Winter 2023.Microbiology (Reading, England) · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohd AtharPhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Silvia GervasoniPhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Andrea CattePhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Andrea BasciuPhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Giuliano MallociPhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Paolo RuggeronePhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
Attilio Vittorio VargiuPhysics Department, University of Cagliari, Cittadella Universitaria, SP 8 km 0.700, 09042, Monserrato (CA), Italy.
University of Cagliari · IT

Funding

Optimization of efflux avoidance and inhibition for antibiotic developmentR01AI136799 · NIAID · UNIVERSITY OF OKLAHOMA · PI GNANAKARAN, SANDRASEGARAM, RUGGERONE, PAOLO · 2018 to 2022
$5.7M
NIAID NIH HHS R01 AI136799
6 · The paper itself

Abstract

Bacterial resistance to antibiotics has been long recognized as a priority to address for human health. Among all micro-organisms, the so-called multi-drug resistant (MDR) bacteria, which are resistant to most, if not all drugs in our current arsenal, are particularly worrisome. The World Health Organization has prioritized the ESKAPE (

Indexed as

Anti-Bacterial AgentsMembrane Transport ProteinsBacterial ProteinsBiological TransportCell DivisionDrug Resistance, Multiple, BacterialHumansAnti-Bacterial AgentsBacterial ProteinsMembrane Transport Proteinsantibioticsbacterial multi-drug resistanceEPIsmolecular dockingmolecular dynamicsRND efflux pumps

Identifiers

PMID36972322
PMCPMC10191380
OpenAlexW4361017309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.