Evidence map›Paper›PMID 36972114›Full record

ArticleJMIR research protocols2023

Prehabilitation Before Gastrointestinal Cancer Surgery: Protocol for an Implementation Study.

Kristy-Lee Raso, Michael Suen, Jane Turner, Sonia Khatri, Yanlan Lin, Carolyn Wildbore, Guillermo Becerril-Martinez, Philip Le Page, Sim Yee Tan, Sam Egger and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR research protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Moving from theory to practice: implementing a prehabilitation program before gastrointestinal cancer surgery (PREHAB-GI).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kristy-Lee RasoDepartment of Nutrition and Dietetics, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0001-8525-9721
Michael Suen *Sydney Medical School, University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0003-3215-0532
Jane Turner *Concord Cancer Centre, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0001-6423-4998
Sonia Khatri *Department of Colorectal Surgery, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0002-3799-1974
Yanlan Lin *Department of Colorectal Surgery, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0002-0968-9292
Carolyn Wildbore *Concord Cancer Centre, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0002-1035-1432
Guillermo Becerril-Martinez *Sydney Medical School, University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0001-5023-6386
Philip Le Page *Department of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0002-0064-2471
Sim Yee Tan *Department of Nutrition and Dietetics, Concord Repatriation General Hospital, Concord, Australia.ORCID https://orcid.org/0000-0002-8188-9395
Sam Egger *The Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council New South Wales, Sydney, Australia.ORCID https://orcid.org/0000-0003-1808-6909
Janette Vardy *Sydney Medical School, University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0002-5739-5790
The University of Sydney · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgery remains the standard curative treatment for early-stage colorectal and upper gastrointestinal cancer. Reduced preoperative functional capacity, nutritional status, and psychological well-being are associated with poor postoperative outcomes. Prehabilitation aims to improve preoperative functional reserves through physical, nutritional, and psychological interventions. Yet, how it transitions from a trial setting to being integrated into a real-world health setting is unknown.

objectiveThe primary aim is to evaluate the implementation of a multimodal (supervised exercise, nutrition, and nursing support) prehabilitation program into standard care for patients with gastrointestinal cancer (colorectal and upper gastrointestinal cancer) scheduled for curative intent surgery. The secondary aim is to determine the impact of a multimodal prehabilitation program on functional capacity, nutritional and psychological status, and surgical outcomes.

methodsThis is an implementation study that will investigate a multimodal prehabilitation intervention, in a nonblinded, nonrandomized, single-group, pre-post design. Patients diagnosed with colorectal and upper gastrointestinal cancer scheduled for potentially curative intent surgery at Concord Repatriation General Hospital, with ≥14 intervention days prior to surgery and are medically cleared to exercise will be eligible. The study will be evaluated using the Reach, Effectiveness, Adoption, Implementation, and Maintenance Evaluation Framework.

resultsThe protocol was approved in December 2019 by the Concord Repatriation General Hospital Human Research Ethics Committee (reference number 2019/PID13679). Recruitment commenced in January 2020. In response to the COVID-19 pandemic, recruitment was paused in March 2020 and reopened in August 2020 with remote or telehealth intervention adaptations. Recruitment ended on December 31, 2021. Over the 16-month recruitment period, a total of 77 participants were recruited.

conclusionsPrehabilitation represents an opportunity to maximize functional capacity and improve surgical outcomes. The study will provide guidance and contribute to the evidence on the integration of prehabilitation into standard care using adaptive models of health care delivery including telehealth.

trial registrationAustralian and New Zealand Clinical Trials Registry ACTR 12620000409976; https://anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378974&isReview=true. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/41101.

Indexed as

cancercolorectalexercisegastrointestinalnutritionprehabilitationpsychologicalsurgerytelehealth

Identifiers

PMID36972114
PMCPMC10131732
OpenAlexW4312371872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.