RevieweLife2023
The role of expectations, control and reward in the development of pain persistence based on a unified model.
Review in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Article
- Efficacy of a mechanism-based psychological intervention for persistent gastrointestinal symptoms in ulcerative colitis and irritable bowel syndrome: results of a three-arm randomised controlled trial (SOMA.GUT-RCT).EClinicalMedicine · 2025Article
- Direct comparisons of neural activity during placebo analgesia and nocebo hyperalgesia between humans and rats.Communications biology · 2025Article
- Increased behavioural inhibition and decreased behavioural activation in whiplash-associated disorders: Associations with health outcomes.European journal of pain (London, England) · 2025Article
- How the magnitude and precision of pain predictions shape pain experiences.European journal of pain (London, England) · 2025Article
- Differential neural activity predicts the long-term stability of the effects of positive and negative expectations on pain.Scientific reports · 2024Article
- A Computational Framework for Understanding the Impact of Prior Experiences on Pain Perception and Neuropathic Pain.PLoS computational biology · 2024Article
- Alcohol use and the pain system.Advances in drug and alcohol research · 2024Review
- Orofacial Pain and Dentistry Management: Guidelines for a More Comprehensive Evidence-Based Approach.Diagnostics (Basel, Switzerland) · 2023Review
- Pain: Behavioural expression and response in an evolutionary framework.Evolution, medicine, and public health · 2023Article
- Perspectives on emotional memory images and the persistence of pain.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic, or persistent pain affects more than 10% of adults in the general population. This makes it one of the major physical and mental health care problems. Although pain is an important acute warning signal that allows the organism to take action before tissue damage occurs, it can become persistent and its role as a warning signal thereby inadequate. Although per definition, pain can only be labeled as persistent after 3 months, the trajectory from acute to persistent pain is likely to be determined very early and might even start at the time of injury. The biopsychosocial model has revolutionized our understanding of chronic pain and paved the way for psychological treatments for persistent pain, which routinely outperform other forms of treatment. This suggests that psychological processes could also be important in shaping the very early trajectory from acute to persistent pain and that targeting these processes could prevent the development of persistent pain. In this review, we develop an integrative model and suggest novel interventions during early pain trajectories, based on predictions from this model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.