ArticleHormones (Athens, Greece)2023
Comparison of insulin resistance-associated parameters in US adults: a cross-sectional study.
Article in Hormones (Athens, Greece), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of triglyceride-glucose index and its related parameters with the risk of stroke: a meta-analysis.BMC neurology · 2025Pooled it
- Associations of Serum Per- and Polyfluoroalkyl Substance Concentrations with Dyslipidemia and Its Subtypes in an Adult Population from Shandong, East China.Environment & health (Washington, D.C.) · 2026Article
- Triglyceride-Glucose Indexes Are Predictive of Early and Severe Diabetic Retinal Microvascular Abnormalities: A Prospective Cohort Study.Ophthalmology science · 2026Article
- Long-term metabolic-adiposity burden and cardiovascular risk: the cumTyG-WHtR in Chinese adults.BMC cardiovascular disorders · 2026Article
- Dynamic Changes in Triglyceride Glucose‒Waist‒to‒Height Ratio and the Risk of Major Adverse Cardiovascular Events: Role of Concurrent Mean Arterial Pressure Change.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Association of TyG index and obesity indicators with cognitive function: a cross - sectional study from Chinese health check-up centers.BMC endocrine disorders · 2026Article
- Article
- Study of the prognostic value of the systemic immune-inflammation index combined with the triglyceride-glucose index in coronary heart disease: a retrospective study based on the MIMIC database.BMC cardiovascular disorders · 2026Article
- Exploring the gut microbiome in type 2 diabetes across different insulin resistance levels: a machine learning approach.Frontiers in nutrition · 2026Article
- Association of TyG-BMI and malnutrition with reduced survival outcomes in patients with cancer: a prospective study.Frontiers in nutrition · 2026Article
- Enhanced prediction of cholecystectomy using obesity-modified TyG indices: a machine learning and SHAP-based study.European journal of medical research · 2025Article
- Comprehensive evaluation of the prevalent insulin resistance indices for pan-cancer incidence and mortality prediction.Tropical medicine and health · 2025Article
- The positive correlation between the triglyceride glucose-body mass index and the presence and severity of early-onset coronary artery disease.Annals of medicine · 2025Article
- Triglyceride-glucose index and its combination with anthropometric obesity indicators are significant predictors of visceral obesity among the Newfoundland population.Scientific reports · 2025Article
- Association between the triglyceride-glucose index and brachial artery flow-mediated dilation function in non-diabetic patients receiving maintenance hemodialysis.BMC nephrology · 2025Article
- Article
- Potential of seven insulin resistance indicators as biomarkers to predict infertility risk in U.S. women of reproductive age: a cross-sectional study.Reproductive biology and endocrinology : RB&E · 2025Article
- Associations between triglyceride-glucose body mass index and all-cause mortality in ICU patients with sepsis and acute heart failure.BMC cardiovascular disorders · 2025Article
- Triglyceride-glucose related indices as predictors for major adverse cardiovascular events and overall mortality in type-2 diabetes mellitus patients.World journal of diabetes · 2025Article
- Association between TyG index with obesity indicators and coronary heart disease: a cohort study.Scientific reports · 2025Article
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Abstract
backgroundTriglyceride-glucose (TyG) is correlated with cardiovascular events caused by insulin resistance (IR). The aim of this study was to analyze the relationship between TyG and its related indicators and IR among US adults from 2007 to 2018 in the National Health and Nutrition Examination Survey (NHANES) database so as to identify more accurate and reliable predictors of IR.
methodsThis is a cross-sectional study including 9884 participants (2255 with IR and 7629 without IR). TyG, TyG-body mass index (TyG-BMI), TyG waist circumference (TyG-WC), and TyG waist-to-height ratio (TyG-WtHR) were measured using standard formulas.
resultsTyG, TyG-BMI, TyG-WC, and TyG-WtHR were significantly correlated with IR in the general population, with TyG-WC being the most strongly correlated, with an odds ratio of 8.00 (95% confidence interval 5.05-12.67) for the fourth quartile of TyG-WC compared with the first quartile in the adjusted model. Receiver operating characteristic (ROC) analysis of the participants showed that the maximum area under the TyG-WC curve was 0.8491, which was significantly higher than that of the other three indicators. Moreover, this trend was stable both among people of both genders and among patients with coronary heart disease (CHD), hypertension, and diabetes.
conclusionsThe present study confirms that the TyG-WC index is more successful than TyG alone in identifying IR. In addition, our findings demonstrate that TyG-WC is a simple and effective marker for screening the general US adult population and those with CHD, hypertension, and diabetes and can be effectively used in clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.