Evidence map›Paper›PMID 36971978›Full record

Observational studyJournal of nephrology2023

Exploring biopsychosocial correlates of pregnancy risk and pregnancy intention in women with chronic kidney disease.

Elizabeth R Ralston, Priscilla Smith, Katherine Clark, Kate Wiles, RaDaR CKD Pregnancy Group, Joseph Chilcot, Kate Bramham

Registry-linked trialFull text readObservational Study
In one paragraph

Observational study in Journal of nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04370769 (Understanding Perception of Risk in Pregnancy Associated Progression of Chronic Kidney Disease), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04370769 unknown statusnot on this map

Understanding Perception of Risk in Pregnancy Associated Progression of Chronic Kidney Disease

TypeobservationalSponsorKing's College LondonRan2020 to 2022Enrolled115ConditionsChronic Kidney Diseases, Pregnancy Related
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Kidney disease and reproductive health.Nature reviews. Nephrology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth R RalstonDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, 5th Floor Addison House, Guy's Campus, London, SE1 1UL, UK. Elizabeth.ralston@kcl.ac.uk.ORCID http://orcid.org/0000-0002-6729-4635
Priscilla SmithDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, 5th Floor Addison House, Guy's Campus, London, SE1 1UL, UK.
Katherine ClarkDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, 5th Floor Addison House, Guy's Campus, London, SE1 1UL, UK.
Kate WilesDepartment of Obstetric Medicine, Bart's and the London NHS Foundation Trust, London, UK.
RaDaR CKD Pregnancy Group
Joseph ChilcotDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Kate BramhamDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, 5th Floor Addison House, Guy's Campus, London, SE1 1UL, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen with Chronic Kidney Disease (CKD) are at increased risk of adverse pregnancy and renal outcomes. It is unknown how women with CKD understand their pregnancy risk. This nine-centre, cross-sectional study aimed to explore how women with CKD perceive their pregnancy risk and its impact on pregnancy intention, and identify associations between biopsychosocial factors and perception of pregnancy risk and intention.

methodsWomen with CKD in the UK completed an online survey measuring their pregnancy preferences; perceived CKD severity; perception of pregnancy risk; pregnancy intention; distress; social support; illness perceptions and quality of life. Clinical data were extracted from local databases. Multivariable regression analyses were performed. Trial registration: NCT04370769.

resultsThree hundred fifteen women participated, with a median estimated glomerular filtration rate (eGFR) of 64 ml/min/1.73m DISCUSSION: Known clinical predictors of pregnancy risk for women with CKD were not associated with women's perceived pregnancy risk nor pregnancy intention. Importance of pregnancy in women with CKD is high, and influences pregnancy intention, whereas perception of pregnancy risk does not.

Indexed as

Quality of LifeRenal Insufficiency, ChronicCross-Sectional StudiesFemaleGlomerular Filtration RateHumansIntentionPregnancyRisk FactorsCKDPregnancyPregnancy intentionRisk perception

Identifiers

PMID36971978
PMCPMC10041500

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read66
identifiers read1
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.